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Healthy Volunteers clinical trials

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NCT ID: NCT01273532 Completed - Healthy Volunteer Clinical Trials

A Study to Compare the Bioequivalence of 50-mg Tapentadol (CG5503) Dose Administered as Two 50-mg Tablets Relative to One 100-mg Tablet

Start date: December 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the bioequivalence of a 100-mg tapentadol (CG5503) dose administered as two 50-mg ER, TRF tablets relative to one 100-mg ER TRF tablet in healthy Japanese male participants.

NCT ID: NCT01273506 Completed - Healthy Volunteer Clinical Trials

A Study to Compare the Bioequivalence of 50-mg Tapentadol (CG5503) Dose Administered as Two 25-mg Tablets Relative to One 50-mg Tablet

Start date: December 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the bioequivalence of a 50-mg tapentadol (CG5503) dose administered as two 25-mg ER, TRF tablets relative to one 50-mg ER TRF tablet in healthy Japanese male participants.

NCT ID: NCT01269762 Completed - Healthy Volunteer Clinical Trials

Pharmacokinetic and Drug Interaction Study of Red Yeast Rice Capsules

Start date: January 2011
Phase: Phase 4
Study type: Interventional

Red yeast rice capsule (LipoCol Forte)is a nature product that has been demonstrated a significant cholesterol lowering effect which might be caused by addictive and/or synergistic effects of lovastatin (monacolin K) with other monacolins and substances in capsules. The usual dose of red yeast rice capsule(LipoCol Forte)for hypercholesterolemia is one capsule twice/day. However, the pharmacokinetic profile of red yeast rice capsule (LipoCol Forte)is still unknown. The objective of the study is to evaluate the pharmacokinetic profile of red yeast rice capsule (LipoCol Forte) after administering single and multiple dose to healthy subjects.

NCT ID: NCT01265108 Completed - Healthy Volunteers Clinical Trials

Effects of Iron on Exercise Capacity During Hypoxia

Start date: November 2010
Phase: Phase 1
Study type: Interventional

During alveolar hypoxia, for example at high altitude or in patients with respiratory disease, there is evidence to suggest that hypoxia-induced pulmonary hypertension might limit exercise performance. Intravenous iron supplementation has recently been shown to reverse pulmonary hypertension in healthy humans at high altitude, and to prevent pulmonary hypertension in volunteers exposed to hypoxia at sea level. The investigators hypothesized that intravenous iron supplementation would enhance exercise capacity during alveolar hypoxia.

NCT ID: NCT01263808 Completed - Healthy Volunteers Clinical Trials

Cardiac Safety of Indacaterol

Start date: April 2008
Phase: Phase 1
Study type: Interventional

This study compares the cardiac safety of inhaled indacaterol with that of placebo and oral moxifloxacin.

NCT ID: NCT01262989 Completed - Healthy Volunteers Clinical Trials

SECOTEX® (Tamsulosin Hydrochloride) Bioequivalence Study Brazil - Fast Admin

Start date: January 2010
Phase: Phase 1
Study type: Interventional

It will be an open-label, randomized, laboratory-blind, crossover study with 02 treatments, 02 sequences, and 02 periods, in which the healthy male volunteers under fasting conditions receive, in each period, the test formulation or the reference formulation

NCT ID: NCT01262794 Completed - Healthy Volunteers Clinical Trials

Pharmacokinetic (PK)/Pharmacodynamic (PD), Study of Single-dose Subcutaneous CDP6038 in Healthy Japanese Male Subjects

Start date: November 2010
Phase: Phase 1
Study type: Interventional

To evaluate the safety and tolerability of CDP6038 following single dose subcutaneous (sc) administration of CDP6038 to Japanese subjects. To evaluate the Pharmacokinetics of CDP6038 following single dose sc administration of CDP6038 to Japanese subjects

NCT ID: NCT01259544 Completed - Healthy Volunteers Clinical Trials

BreathID® Test: A Non-invasive Modality to Detect Pancreatic Exocrine Insufficiency

Start date: January 2009
Phase: Phase 2
Study type: Interventional

13C breath di-peptide tests are an effective non-invasive tool to detect pancreatic exocrine function in patients with Chronic Pancreatitis.

NCT ID: NCT01258777 Completed - Healthy Volunteers Clinical Trials

A Study of the Pharmacokinetics of Golimumab in Japanese and Caucasian Male Subjects

Start date: October 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics of golimumab in Japanese and Caucasian Males.

NCT ID: NCT01255501 Completed - Healthy Volunteers Clinical Trials

First in Human Study of NI-0701 in Healthy Volunteers

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety, pharmacodynamic and pharmacokinetic profiles of a novel therapeutic drug when administered to healthy volunteers.