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Healthy Volunteers clinical trials

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NCT ID: NCT02253056 Completed - Healthy Volunteers Clinical Trials

Monday is Fasting Day - Non-Randomized Trial on Intermittent Fasting

MIFT
Start date: September 2014
Phase: N/A
Study type: Interventional

The aim of this pilot study is to evaluate the effects of one regular fasting day per week over a total period of 8 weeks compared to a normal-eating habits among healthy volunteers.

NCT ID: NCT02252354 Completed - Healthy Volunteers Clinical Trials

TAK-385 Phase I Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability Study

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this 2 part study is to look at how TAK-385 is taken up, broken down and removed from the body when given as a radiolabelled oral solution (by mouth) or as an oral tablet (by mouth) followed by a radiolabelled intravenous (IV) infusion (into the arm vein).

NCT ID: NCT02249728 Completed - Healthy Volunteers Clinical Trials

Absorption, Metabolism and Excretion Study of [14C]PBT2 and Absolute Bioavailability of PBT2

Start date: June 2014
Phase: Phase 1
Study type: Interventional

The purpose of the study is to investigate how the test drug, PBT2, is taken up, broken down and removed from the body when given as an oral capsule, a radiolabelled oral suspension and a radiolabelled intravenous injection.

NCT ID: NCT02248818 Completed - Healthy Volunteers Clinical Trials

AZD8108 SAD/MAD in Healthy Volunteers

AZD8108
Start date: November 2014
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, placebo-controlled study of single and multiple ascending dosage levels of AZD8108 in healthy volunteers. The study includes an up to 28-day screening period, an in-house period during which AZD8108 or placebo will be administered orally as a solution, and a 4- to 10-day follow-up period after discharge.

NCT ID: NCT02247765 Completed - Healthy Volunteers Clinical Trials

Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion

Start date: November 2014
Phase: N/A
Study type: Observational

To validate the proposed claims for pulse rate and saturation accuracy in a diverse subject population during motion over a specified saturation range.

NCT ID: NCT02243683 Completed - Healthy Volunteers Clinical Trials

Safety Study of Immune System Modulator for Autoimmune Diseases

Start date: September 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the toxicity, tolerability and safety of single ascending doses of AX-024.HCl in healthy male subjects.

NCT ID: NCT02243150 Completed - Healthy Volunteers Clinical Trials

Safety, Pharmacokinetic and Pharmacodynamic Study of the CDK 4/6 Inhibitor G1T28-1

Start date: September 2014
Phase: Phase 1
Study type: Interventional

This first-in-human (FIH) study will provide the first safety, PK, and PD data of G1T28-1 in humans and will allow further development of G1T28 1 in patients with cancer to reduce chemotherapy-induced myelosuppression.

NCT ID: NCT02242981 Completed - Healthy Volunteers Clinical Trials

A Study of How the Body Breaks Down and Eliminates LY2623091

Start date: September 2014
Phase: Phase 1
Study type: Interventional

This type of study is called a radiolabeled study. For this study, LY2623091 (study drug) has been specially prepared to contain radiolabeled carbon [^14C]. [^14C] is a naturally occurring radioactive form of the element, carbon. This study will increase understanding about how the drug appears in the blood, urine, and stool after it is administered to healthy participants. Information about any side effects that may occur will also be collected. This study will last up to 22 days for each participant, not including screening. Screening is required within 28 days prior to enrollment

NCT ID: NCT02242903 Completed - Healthy Volunteers Clinical Trials

A Study of LY3079514 in Healthy Participants

Start date: October 2014
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and how well the body will handle a single dose of study drug, LY3079514. This study will last about 12 weeks for each participant.

NCT ID: NCT02238782 Completed - Clinical trials for Healthy Volunteers Bioavailability Study

A Study to Assess the Absolute Bioavailability of Oral Selumetinib in Healthy Male Volunteers.

Start date: October 2014
Phase: Phase 1
Study type: Interventional

To assess the absolute bioavailability of oral selumetinib in healthy male volunteers