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Clinical Trial Summary

To assess the D1 receptor occupancy (D1 RO) in striatum after a single oral administration of PF-06412562.


Clinical Trial Description

Primary Objectives:

- To assess the D1 receptor occupancy (D1 RO) in striatum after a single oral administration of PF-06412562

- To assess the relationship of D1 RO in the striatum versus plasma exposure of PF-06412562 after a single oral administration.

Secondary Objective:

• To evaluate the plasma exposure of PF-06412562for the duration of PET scan following a single oral administration of PF-06412562.

Safety Objectives:

• To evaluate the safety and tolerability of PF-06412562 of single oral doses of PF-06412562. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03686501
Study type Interventional
Source Invicro
Contact
Status Completed
Phase Early Phase 1
Start date September 10, 2018
Completion date March 28, 2019

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