Healthy Elderly Clinical Trial
Official title:
Reference Values of Cerebrospinal Fluid Outflow Resistance and Intracranial Pressure in Healthy Elderly
Objective. The intracranial pressure and cerebrospinal outflow resistance are essential
parameters to describe the cerebrospinal fluid dynamic system. Outflow resistance effects
intracranial pressure, pulse amplitudes, cerebrospinal fluid absorption as well as the
compliance of the system. The objective of this study was to determine the reference values
in the elderly.
Methods. Elderly people (60-82 years), considering themselves healthy, were recruited
through an ad in the local paper. All were evaluated with a 3 Tesla magnetic resonance
imaging apparatus. Subjects were eligible if they did not have any psychiatric or
neurological disorder or signs of advanced atherosclerotic disease. Intracranial pressure
and outflow resistance were determined by a constant pressure infusion method with the
patient in the supine position. The study population consisted of 40 subjects (mean age 70
years; 23 women).
n/a
Observational Model: Case-Only, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04795284 -
Biomechanical Parameters of Gait in Patients With Symptomatic Lumbar Spinal Stenosis and Healthy Elderly.
|
||
| Completed |
NCT02235168 -
Effect of Rollator on Walking Distance in Elderly Patients
|
N/A | |
| Terminated |
NCT01421446 -
Study to Validate a Computerized Neuropsychological Test Battery
|
N/A | |
| Completed |
NCT03536871 -
Exercise and Nutritional Supplementation
|
N/A | |
| Recruiting |
NCT03691129 -
Yoga Efficacy and Bioactive Materials in the Blood of Korean Elderly
|
N/A | |
| Completed |
NCT02376270 -
Pectin, Aging and Intestinal Barrier Function
|
Phase 4 | |
| Terminated |
NCT02170012 -
A Study In Healthy Elderly People To Evaluate Safety, Toleration, Pharmacokinetics and Pharmacodynamics of Multiple Oral Doses Of PF-06743649
|
Phase 1 | |
| Completed |
NCT04028648 -
Generation of Prediction Equations for BIA of the Elderly
|
||
| Completed |
NCT02036645 -
SAD/MAD Study to Assess Safety, Tolerability, PK & PD of MEDI1814 in Subjects With Mild-Moderate Alzheimer's Disease.
|
Phase 1 | |
| Completed |
NCT02063646 -
Effect of a Polyphenol-rich Food Supplement on Cognitive Function in Healthy Aging Adults
|
N/A | |
| Completed |
NCT04350177 -
A Study to Assess Single and Multiple Doses of IkT-148009 in Healthy Elderly Participants and Parkinson's Patients
|
Phase 1 | |
| Recruiting |
NCT05827653 -
MAD Study of NX210c
|
Phase 1 | |
| Completed |
NCT00931814 -
Effects of Exercise on Depression Symptoms, Physical Function, and Quality of Life in Community-Dwelling Elderly
|
N/A | |
| Withdrawn |
NCT02765425 -
Training the Brain With a Robotic Device for Balance Recovery
|
N/A | |
| Completed |
NCT02125305 -
Clinical Study to Investigate the Pharmacokinetics and Pharmacodynamics of Metformin in the Elderly
|
Phase 1 | |
| Suspended |
NCT04086589 -
Restoring Molecular Circadian Rhythm
|