Healthy Diet Clinical Trial
Official title:
Health Effects of Cetoleic Acid (Helseeffekter av Ketolinsyre)
In this Randomized Controlled Trial (RCT) we want to study how supplements of cetoleic acid ( C22:n1-11) (intervention) affect the conversion of alpha-linolenic acid (ALA) to EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) in healthy subjects, compared to supplements with a low concentration of cetoleic acid (control). Our primary endpoints are changes in the concentration of EPA and DHA in plasma and red blood cells.
This is a randomized double-blinded controlled trial ( randomized 1:1). Study population: healthy men and women 20-70 years, BMI 20-35 kg/m2. Study design: - 3 weeks run-in-period where all participants consume control capsules every morning. - Randomization intervention: control (1:1). All participants consume their capsules (control or intervention) for 4 weeks. The intervention oil consists of a fish oil high in cetoleic acid and the control oil is a mix of different oils and low in cetoleic acid. Power calculation and sample size: It was expected a difference of 15% in n-3 between the groups after the intervention (Østbye et al. 2019, doi:10.1017/S0007114519001478). The level of significance was set to 5% (two-sided) and the power to 80%. A total of thirty-eight subjects were required to participate in the study, but a high dropout rate was expected (20%) and it was considered necessary to include a total of seventy (n=70) subjects (thirty-five per arm). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04506996 -
Monday-Focused Tailored Rapid Interactive Mobile Messaging for Weight Management 2
|
N/A | |
| Not yet recruiting |
NCT05218980 -
Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health
|
N/A | |
| Not yet recruiting |
NCT04119791 -
A Multidisciplinary Investigation of Cardiovascular Benefits of Wild Rice
|
N/A | |
| Recruiting |
NCT05660837 -
Online Social Support Program for Physical and Mental Health of Filipino Migrant Domestic Workers in Hong Kong
|
N/A | |
| Completed |
NCT05098223 -
Price Promotions on Purchases of Snacks
|
N/A | |
| Active, not recruiting |
NCT05400187 -
Body Composition Assessment and Smart-phone Based Counselling on Healthy Eating and Weight Management
|
N/A | |
| Completed |
NCT03941392 -
Nutritional Study in Spanish Pediatric Population
|
||
| Completed |
NCT03378843 -
Spermidine Intake and All-cause Mortality
|
N/A | |
| Completed |
NCT04596254 -
Detection of Gut Metabolites in Mother's Milk Following Juice Intake
|
N/A | |
| Completed |
NCT04078646 -
Influence of Proteins on the Bioavailability of Carotenoids
|
N/A | |
| Completed |
NCT05351853 -
Metabolic Effects of Plant-based Diet
|
N/A | |
| Completed |
NCT04275843 -
The Effects of Western Diet Patterns on Plasma Inflammatory and Cardio Metabolic Health Signatures in Middle-aged Adults
|
N/A | |
| Completed |
NCT05619276 -
Acute Intervention to Assess the Impact of Practical Strategies for Healthy Eating
|
N/A | |
| Recruiting |
NCT05290064 -
Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism
|
N/A | |
| Completed |
NCT06119165 -
Impact of Environmental Nudges on Dietary Quality
|
N/A | |
| Completed |
NCT03967912 -
MOVE UP Lifestyle Intervention for Caregivers
|
N/A | |
| Recruiting |
NCT05657730 -
Study the Effect of Water Kefir Consumption on the Gut Microbiome in Healthy Adults
|
N/A | |
| Completed |
NCT05213273 -
Nutritional Study on the Beneficial Effects of Canned Fish Consumption on Healthy Adult Population
|
N/A | |
| Active, not recruiting |
NCT04329962 -
Metabolism and Absorption of Anthocyanins From Extract and Whole Blueberry Powder Confections in Healthy Adults
|
N/A | |
| Recruiting |
NCT04299685 -
Family Factors of Eating Habits Among Adolescents
|