Healthy Adults Clinical Trial
— Co-ACT&LEARNOfficial title:
Effects of Dual-Task Training on Cognitive and Motor Learning and Cortical Activation in Healthy Young Adults
Verified date | January 2022 |
Source | East Carolina University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this research study is to assess the effects of dual-task training using a dynamic balance task and an auditory reaction time task on dual-task performance in healthy young adults and to assess the cortical activity within the prefrontal and sensorimotor cortices in response to dual-task training using functional near infrared spectroscopy (fNIRS).
Status | Completed |
Enrollment | 18 |
Est. completion date | November 30, 2021 |
Est. primary completion date | August 30, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility | Inclusion Criteria: 1. Healthy young adults 2. Right-handed Exclusion Criteria: 1. Individuals with cognitive deficits or communication problems 2. Individuals with impaired vision 3. Individuals with balance disorders such as vestibular disorders, etc. 4. Individuals with known cardiorespiratory dysfunctions 5. Individuals with presence of lower extremity condition, injury, or surgery within last 3 months which could compromise training 6. Individuals with history of concussion |
Country | Name | City | State |
---|---|---|---|
United States | East Carolina University | Greenville | North Carolina |
Lead Sponsor | Collaborator |
---|---|
East Carolina University |
United States,
Beauchet O, Dubost V, Herrmann FR, Kressig RW. Stride-to-stride variability while backward counting among healthy young adults. J Neuroeng Rehabil. 2005 Aug 11;2:26. — View Citation
Fraser SA, Li KZ, Berryman N, Desjardins-Crépeau L, Lussier M, Vadaga K, Lehr L, Minh Vu TT, Bosquet L, Bherer L. Does Combined Physical and Cognitive Training Improve Dual-Task Balance and Gait Outcomes in Sedentary Older Adults? Front Hum Neurosci. 2017 Jan 18;10:688. doi: 10.3389/fnhum.2016.00688. eCollection 2016. — View Citation
Ghai S, Ghai I, Effenberg AO. Effects of dual tasks and dual-task training on postural stability: a systematic review and meta-analysis. Clin Interv Aging. 2017 Mar 23;12:557-577. doi: 10.2147/CIA.S125201. eCollection 2017. Review. — View Citation
Kiss R, Brueckner D, Muehlbauer T. Effects of Single Compared to Dual Task Practice on Learning a Dynamic Balance Task in Young Adults. Front Psychol. 2018 Mar 12;9:311. doi: 10.3389/fpsyg.2018.00311. eCollection 2018. — View Citation
Pinti P, Tachtsidis I, Hamilton A, Hirsch J, Aichelburg C, Gilbert S, Burgess PW. The present and future use of functional near-infrared spectroscopy (fNIRS) for cognitive neuroscience. Ann N Y Acad Sci. 2020 Mar;1464(1):5-29. doi: 10.1111/nyas.13948. Epub 2018 Aug 7. Review. — View Citation
Techayusukcharoen R, Iida S, Aoki C. Observing brain function via functional near-infrared spectroscopy during cognitive program training (dual task) in young people. J Phys Ther Sci. 2019 Jul;31(7):550-555. doi: 10.1589/jpts.31.550. Epub 2019 Jul 9. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in auditory reaction time task performance | Average amount of time in seconds for a button press in response to an auditory tone | Baseline to 10 days, and upto 3 weeks. Shorter reaction time indicates better performance. | |
Primary | Change in balance task performance | The average amount of time in seconds that a participant maintains the stability platform within 3 degrees of horizontal position during 6 trials of 30 sec each. The total score will range between 0-30 s. Higher balance score indicates better balance performance. | Baseline to 10 days, and upto 3 weeks | |
Primary | Change in dual-task performance | Dual-task performance will assess performance on the combined auditory reaction time task and the balance task, i.e. performance under influence of dual-task situation. | Baseline to 10 days, and upto 3 weeks | |
Primary | Change in Cortical Activation | The amount of change in cortical activity (change in oxyhemoglobin concentration in umol) within the prefrontal and sensorimotor cortices in response to dual-task training. | Baseline to 10 days, and upto 3 weeks | |
Secondary | Errors in auditory reaction time task performance | Error is a wrong button pressed in response to the auditory tone | Baseline to 10 days, and upto 3 weeks | |
Secondary | Balance variability | The average amount of time in seconds on the left and right side of the dynamic stability platform outside of 3 degrees in the center during 6 trials of 30 seconds each. Smaller time on the right and left side indicates improvement in variability. | Baseline to 10 days, and upto 3 weeks |
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