Effects of High-intensity Interval Training in Combination With Side-alternating Whole-body Vibration

Health Behavior Clinical Trial

Official title:

Effects of High-intensity Interval Training in Combination With Side-alternating Whole-body Vibration

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01875146
• Other study ID #: vyc
• Status: Completed
• Phase: N/A
• First received: May 16, 2013
• Last updated: January 6, 2014
• Start date: January 2013
• Est. completion date: December 2013

Study information

• Verified date: December 2013
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: Ethikkommission
• Study type: Interventional

Clinical Trial Summary

Investigation of the training effects following 8 weeks of high-intensity interval training (HIT)in combination with side-alternating whole-body vibration compared to conventional HIT or side-alternating whole-body vibration. The adaptations are investigated on a molecular (muscle biopsy of the M. vastus lateralis) and systemic (e.g. cycling, jumping mechanography, dynamometry) level. In addition, the acute effects of the first and last training session will be investigated on a molecular (e.g. satellite cell activation, mRNA abundance) and systemic (e.g. ventilatory ga exchange, heart rate, rating of perceived exertion) level.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 33
• Est. completion date: December 2013
• Est. primary completion date: December 2013
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 18 Years to 35 Years

Eligibility

Inclusion criteria: - male

• no fever / no common cold at the beginning of the study

• between 18 and 35 years of age

• non-smoker

• no known cardiovascular or orthopedic problems

• no cardiac pacemaker

• fullfills healts questionnaire's requirements

Exclusion criteria: - female

• fever / common cold at beginning of study

• age under 18 oder above 35y

• smoker

• cardiovascular or orthopedic problems

• cardiac pacemaker

• does not fullfill health questionnaire's requirements

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Health Behavior

Intervention

Other:
• 4x4 min HIT
Conventional 4x4 min high-intensity interval training
• 4x4 min HIT + WBV (18 Hz)
4x4 min high-intensity interval training in combination with whole-body vibration at 18 Hz during the active rest
• 4x4 min HIT + (30 Hz)
4x4 min high-intensity interval training in combination with whole-body vibration at 30 Hz during the active rest
• whole-body vibration at 30 Hz
4x3 min whole-body vibration at 30 Hz

Locations

Country	Name	City	State
Switzerland	University Hospital Zurich, Division of Neurology	Zurich	ZH

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from baseline in Critical Power	The differences in changes in Critical Power [Watts] are compared between the 4 training groups. For this purpose, participants complete before and after the training intervention an incremental cycling ramp test and 4 cycling constant-load tests.	8 weeks intervention	No