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Headache clinical trials

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NCT ID: NCT01316471 Completed - Chronic Pain Clinical Trials

Internet Intervention for Adolescents With Chronic Pain

Start date: May 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy of a web-based (i.e., internet) behavioral program to reduce pain and improve functioning in children and adolescents with chronic pain. We hypothesize that children and adolescents in families that receive the web-based behavioral program will report reduced pain levels and improved daily functioning compared to children and their parents who receive online patient education.

NCT ID: NCT01314768 Completed - Chronic Headache Clinical Trials

Brief Intervention for Medication Overuse Headache

BIMOH
Start date: March 2011
Phase: N/A
Study type: Interventional

The investigators will perform a cluster randomised controlled study of Brief intervention (BI) for medication-overuse headache (MOH) versus business as usual. GPs will be trained to perform a structured brief intervention after identifying patients with probable MOH using the severity of dependence scale. The control arm will include patients of GPs who have not been trained in BI. Patients will be recruited by prior short postal screening of patients listed on the GPs patient lists. The hypothesis is that BI will lead to improvement of medication-overuse and chronic headache as compared to no BI. Main outcomes are: - number of medication days per month - number of headache days per month - headache index

NCT ID: NCT01306266 Withdrawn - Clinical trials for Chronic Post-traumatic Headache

Study of Rizatriptan in the Treatment of Acute Attacks of Post-traumatic Headache in U.S. Military Troops

Maxalt
Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effectiveness of rizatriptan for treating attacks of chronic post-traumatic headache.

NCT ID: NCT01298921 Terminated - Cluster Headache Clinical Trials

A Pilot Study of Demand Valve Oxygen Inhalation Therapy for Cluster Headache

Start date: January 2011
Phase: Phase 1
Study type: Interventional

Cluster headache is a disorder marked by frequent attacks of short-lasting, severe, unilateral head pain with associated autonomic symptoms. It is the most severe head pain syndrome known. Currently, the two most common treatments for cluster headaches are inhaled oxygen and injectable sumatriptan. These treatments do not work for all cluster headache patients, and patients who smoke may eventually develop contraindication to triptans. New treatment options are needed. An alternative method of oxygen delivery (as opposed to continuous flow) uses a demand valve that is controlled by respiration rate, allowing increased oxygen flow in response to increased demand. This system may be more efficacious at stopping a cluster headache attack than the currently prescribed oxygen delivery system. This study will compare the effectiveness of oxygen delivered via demand valve versus continuous high flow oxygen via non-rebreather face mask in the acute treatment of a cluster headache attack. All patients will treat one cluster headache with each of the 2 treatment methods.

NCT ID: NCT01294046 Completed - Migraine Headache Clinical Trials

Electrical Stimulation of the Sphenopalatine Ganglion for the Treatment of Migraine Headaches

Start date: March 2011
Phase: N/A
Study type: Interventional

This investigation will gather information about a procedure called sphenopalatine ganglion (SPG) stimulation, and its appropriateness, safety, and efficacy as a treatment for those who suffer migraine headaches which may result in chronic severe disability. The SPG is a small collection of nerve cells in the head, and is located near the base of the nose on either side. Participation involves the surgical implantation of an electrode (small electrical conductor) over the sphenopalatine ganglion. The electrode is connected to a stimulator which will enable treatment for migraine headaches. Tiny electrical current is delivered to the stimulator device by an internal pulse generator implanted in the area at the top of the chest, to stop the migraine headaches. The implant system will be controlled with a wireless remote provided after the implant procedure. Participation will record headache diaries throughout the study, which will last approximately 8½ months, and a yearly visit annually for five years.

NCT ID: NCT01288781 Completed - Clinical trials for High Altitude Headache

Intracranial Pressure in Experimental Models of Headache

Start date: July 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether increased pressure in the head is elevated in people who suffer from High Altitude Headache. We hypothesise that head pressure will be elevated in people with High Altitude Headache.

NCT ID: NCT01276977 Completed - Migraine Headache Clinical Trials

Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine

Start date: April 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to Compare the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet in the acute treatment of migraine. To develop and evaluate a set of importance weights for a predefined set of treatment attributes for migraine suffers using zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet. To contrast the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet at early time points. To analyze the patterns of self-reported tolerability of migraine sufferers using zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet.

NCT ID: NCT01255813 Completed - Clinical trials for Chronic Cluster Headache

Sphenopalatine Ganglion Stimulation for the Acute Treatment of Cluster Headache

Start date: December 2010
Phase: N/A
Study type: Interventional

The purpose of the proposed clinical study is to evaluate the use of an implanted Neurostimulator to provide Sphenopalatine Ganglion (SPG) stimulation for the management of the pain associated with cluster headaches.

NCT ID: NCT01244555 Completed - Clinical trials for Tension-type Headache

Muscle Treatment for Management of Pain & Disability in Tension-type Headache

Start date: April 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of treatments (massage therapy or ultrasound) directed at skeletal muscle for alleviating pain associated wtih tension headache.

NCT ID: NCT01216358 Completed - Headache Clinical Trials

Boston Migraine and Contraception Study

BMAC
Start date: October 2010
Phase: N/A
Study type: Observational

The objectives of this prospective, descriptive study are to: 1. generate estimates of the incidence, prevalence, persistence, clinical impact and attributable risk of migraine due to hormonal contraception (HC) use; and 2. identify predictive factors for clinically significant changes in headache attributable to HC use. The investigators hypothesize that: 1. Most women with pre-existing migraine will have no significant change from baseline headache frequency or clinical impact attributable to HC at 3 months following initiation; a minority will report clinically significant worsening or improvement 2. The incidence of headache and migraine in HC users will not be significantly different from their incidence in NHC users 3. There will be identifiable risk factors for development or worsening of headache/migraine in the minority of HC users where that occurs.