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Headache clinical trials

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NCT ID: NCT04674020 Recruiting - Migraine Clinical Trials

Registry for Migraine - Structural and Functional MRI Before and After Erenumab Treatment

REFORM
Start date: October 22, 2020
Phase: Phase 4
Study type: Interventional

This study aims to investigate structural and functional cerebral changes using magnetic resonance imaging before and after treatment with erenumab in patients with migraine.

NCT ID: NCT04672044 Recruiting - Clinical trials for Chronic Post-stroke Headache

TMS and Exercise for Post-stroke Pain

Start date: January 14, 2022
Phase: Phase 1
Study type: Interventional

There are over 7 million people living with stroke in the United States. Per year, approximately 17,000 Veterans are admitted to the VA for acute stroke. Chronic pain after stroke can occur between 10-50% of stroke survivors. Post-stroke pain (PSP) can lead to further complications in a stroke survivor's recovery. Exercise has improved PSP and associated symptoms such as mobility, fatigue, and quality of life. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive technique using electromagnetic induction for cortical neurostimulation. The use of rTMS has been explored shown to be effective in treating chronic PSP but is limited in effect duration. Our proposal will test the hypothesis that rTMS is feasible and safe to be paired with exercise. Additionally, the investigators believe a complementary effect can develop to enhance the neurostimulation duration of rTMS.

NCT ID: NCT04662125 Completed - Analgesia Clinical Trials

Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin

Start date: December 10, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects of prednisolone and pregabalin in patients undergoing lower limb surgery.

NCT ID: NCT04660864 Completed - Migraine Clinical Trials

Nasal Cavity Cooling for the Symptomatic Relief of Migraine Headache - a Pilot Study

Start date: March 3, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effect of self-administered intranasal cooling for the symptomatic relief of migraine headache and associated symptoms in an "at home setting". 10-20 patients - who have been diagnosed according to the International Classification of Headache disorders (2nd Edition) criteria for Episodic migraine, with or without aura - will be included in the study. During a screening period of one month participants will record their migraine symptoms, any treatment and treatment effects. After a minimum om two migraine attacks the participants receive individual instructions on how to use the The RhinoChill® system. During the following treatment period of the study, participants are instructed to treat their upcoming three migraine attacks with 10 minutes of nasal cavity cooling according to the instructions and thereby register symptoms and treatment effects after 10 minutes, 1 hour, 2 hours, 24 hours and 48 hours.

NCT ID: NCT04657952 Not yet recruiting - Clinical trials for Post-Dural Puncture Headache

Sphenopalatine Ganglion Block for Post-Dural Puncture Headache in Orthopedic Patients

Start date: December 10, 2020
Phase: Phase 4
Study type: Interventional

The aim of this study is to assess the efficacy, onset and duration of analgesia of sphenopalatine ganglion bock (SPGB) using lidocaine 4% with adrenaline as a treatment of postoperative Post dural puncture headache (PDPH) of orthopedic patients after lower limbs surgeries.

NCT ID: NCT04650282 Terminated - Headache Clinical Trials

Sphenopalatine Ganglion Block for Headache After Concussion

Start date: March 18, 2021
Phase: Phase 2
Study type: Interventional

This clinical trial will enroll participants to evaluate the effects of SPG block on post-traumatic headache. The study hypothesizes that patients that receive a SPG block with lidocaine vs. placebo (saline) will have a lower number of headache days in the week following the procedure, and will also report lower symptom scores. Eligible participants will receive one treatment (SPG block) as well as complete surveys prior to and after receiving treatment (for a total of approximately 2 weeks).

NCT ID: NCT04636034 Terminated - Covid19 Clinical Trials

The Effect of Ganglion Sphenopalatine Block Versus Placebo on Persistent Headache Following COVID-19 Infection

Start date: January 12, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of the ganglion sphenopalatine block (SPG block) on persistent headache following acute COVID-19 infection.

NCT ID: NCT04632420 Completed - Headache Clinical Trials

Evaluation of Headache and Childbirth in a Chronic Pain Population

Start date: September 13, 2019
Phase:
Study type: Observational

Headache and backache are common symptoms following childbirth. The incidence of these symptoms have been shown to increase during the postpartum period between 5 to 12 months following delivery. By 12 months postpartum up to 45% and 65% of women experience headache and backache, respectively. While studies have reported headache and backache as frequently persistent symptoms beyond the first year postpartum, few studies have specifically interrogated women seeking specialist pain physician input or identified predisposing risk factors. Finally there is little known about typically described pain characteristics of women who suffer with chronic postpartum headache and backache. We aim to compare the prevalence of chronic headache in women that have versus have not experienced childbirth.

NCT ID: NCT04629573 Completed - Clinical trials for Epidural; Anesthesia, Headache

Epidural Anesthesia and Myomectomy Associated Bleeding

Start date: June 2014
Phase: N/A
Study type: Interventional

This is a prospective study for abdominal myomectomies performed from June 2012 to June 2019 by a single surgeon in a tertiary care referral hospital. Large uterine myoma was defined as the estimated diameter of dominant myoma equal to or larger than 10 cm by sonography. Demographics, diagnosis, perioperative variables, operative outcomes and complications were recorded. The Intraoperative anesthetic management, blood and blood products transfusion, and total volume of blood loss, as well as postoperative follow-up, were reviewed for each patient.

NCT ID: NCT04625387 Completed - Clinical trials for Cervicogenic Headache

Dry Needle In Management of Cervicogenic Headache

Start date: May 15, 2020
Phase: N/A
Study type: Interventional

Headache is an important health problem. It is the commonest type of all signs of illness in the people worldwide. Cervicogenic Headache is commonest musculoskeletal condition in physiotherapy practice. This study's main objective was to evaluate effectiveness of Dry Needle with exercise in decreasing pain and improving function in patients with Cervicogenic Headache.