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Value of FLT-PET Before and During Radiotherapy in Head and Neck Tumors

Head and Neck Neoplasms Clinical Trial

Official title:
Value of FLT-PET Before and During Radiotherapy in Head and Neck Tumors

Clinical Trial Summary

Tumor cell proliferation and repopulation contribute to resistance to radiotherapy in head and neck cancer. Up to now, this characteristic is mostly assessed using biopsies acquired during inspection under general anaesthesia before treatment.

18F-FLT-PET (positron emission tomography) is a non-invasive imaging method showing areas of active proliferation. The aim of this study is to assess the value of the functional information gained by 18F-FLT-PET for radiotherapy planning and early tumor response assessment.

Prior to radiotherapy, a planning CT-scan and a 18F-FLT-PET scan are acquired. After approximately two weeks of radiotherapy a further PET scan is obtained.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00163176
Study type Observational
Source Radboud University
Contact
Status Completed
Phase Phase 1
Start date July 2005
Completion date December 2010
View Details
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