Clinical Trials Logo
  1. Home
  2. Head and Neck Cancers
  3. NCT00186433
  4. Details
NCT00186433 Clinical Trial

A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations

Head and Neck Cancers Clinical Trial

Official title:
A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00186433
Other study ID # ENT0006
Secondary ID ENT000677622
Status Completed
Phase N/A
First received September 13, 2005
Last updated May 22, 2015
Start date November 2001
Est. completion date June 2013

Study information
Verified date May 2015
Source Stanford University
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

1. To determine the prognostic implication of plasma Epstein-Bar Virus (EBV) DNA concentrations, as measured by quantitative polymerase chain reaction (PCR) in patients with nasopharyngeal carcinoma (NPC).

2. To relate pretreatment plasma EBV DNA concentration to WHO classification of these tumors both in endemic and non-endemic areas.

3. To determine whether pretreatment plasma EBV DNA can serve as a prognostic factor for both endemic and non-endemic patient populations.

Recruitment information / eligibility
Status Completed
Enrollment 49
Est. completion date June 2013
Est. primary completion date June 2013
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Having a new diagnosis of Nasopharyngeal carcinoma.

- Being treated with either radiotherapy or chemoradiotherapy for this condition.

Exclusion Criteria:

- Age <18 since NPC is a very rare condition in this age group and may have a different biological behavior

- Patients who are unable to provide informed consents for themselves.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
United States Stanford University School of Medicine Stanford California

Sponsors (1)
Lead Sponsor Collaborator
Stanford University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Plasma Epstein-Bar Virus (EBV) DNA concentrations measured by quantitative polymerase chain reaction (PCR) every 6 months until end of study No
See also
  Status Clinical Trial Phase
Terminated NCT00721539 - Assessing the da Vinci® Robotic Surgical System for Surgery of the Upper Aerodigestive Tract N/A
Recruiting NCT00568490 - Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
Completed NCT01135849 - B-Receptor Signaling in Cardiomyopathy N/A
Completed NCT00313027 - Cervical Nodal Mets in Squamous Cell Carcinoma of H&N - MRI, FDG-PET, & Histopathologic Correlation N/A
Recruiting NCT02997332 - Durvalumab in Combination With Docetaxel, Cisplatin and 5-FU for Locally Advanced Head and Neck Squamous Cell Carcinoma Phase 1
Completed NCT02854358 - Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia Phase 2
Terminated NCT01114256 - FNA Tumor Sampling for CD137 Modulation: A Pilot Study N/A
Terminated NCT00965003 - MRI Laryngeal Imaging With a Surface Coil Early Phase 1
Active, not recruiting NCT00490061 - Phase II Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy Phase 2
Recruiting NCT05122221 - CRTE7A2-01 TCR-T Cell for HPV-16 Positive Advanced Cervical, Anal, or Head and Neck Cancers Phase 1
Completed NCT02045368 - Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R Phase 1
Completed NCT01908504 - Adaptive Pet Study N/A
Completed NCT05648682 - Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis N/A
Not yet recruiting NCT03394417 - StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers Patients N/A
Active, not recruiting NCT00580203 - Collection Of Tissue, Blood, and Other Specimens From Patients With Head and Neck Tumors To Study the Causes, Diagnosis, Prevention and Treatment of Cancers
Completed NCT00230295 - Indirect Magnetic Resonance Lymphangiography of the Head and Neck Region Using Conventional Gadolinium-based Contrast N/A
Completed NCT00610415 - Biopsy of Human Tumors for Cancer Stem Cell Characterization: a Feasibility Study N/A
Completed NCT01664936 - Non-Invasive Cerenkov Luminescence Imaging of Lymphoma, Leukemia and Metastatic Lymph Nodes
Completed NCT01163487 - Metabolic Reprogramming Therapy for Treatment of Recurrent Head and Neck Cancers Phase 1
Terminated NCT01137162 - Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors N/A