Head and Neck Cancer Clinical Trial
Official title:
Prediction of Overall Survival Using Mass Spectrometry Profiling in Head and Neck Cancer Patients Treated With Epidermal Growth Factor Receptor Inhibitors
RATIONALE: Studying samples of blood in the laboratory from patients with cancer may help
doctors learn more about changes that occur in DNA and identify biomarkers related to
cancer. It may also help doctors predict how patients will respond to treatment.
PURPOSE: This research study is looking at blood sample analysis in predicting overall
survival in patients with recurrent or metastatic head and neck cancer.
OBJECTIVES:
- To validate the mass spectrometry profile that is predictive of survival benefit in
patients with recurrent or metastatic head and neck squamous cell carcinoma treated
with EGFR inhibitors.
OUTLINE: Plasma and serum samples are analyzed by matrix-assisted laser
desorption/ionization time-of-flight mass spectrometry and classified according to prognosis
("good" vs "poor") using a previously developed predictive algorithm.
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