Head and Neck Cancer Clinical Trial
Official title:
Survival Prediction in HNSCC Based on Gene Expression Profiles From FFPE Tissues
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may
help doctors learn more about changes that occur in DNA and identify biomarkers related to
cancer. It may also help doctors predict survival of patients with head and neck cancer.
PURPOSE: This laboratory study is assessing gene expression profiles in predicting survival
of patients with head and neck cancer.
OBJECTIVES:
- Identify gene expression profiles associated with survival by DNA microarray assay
analysis using RNA from formalin-fixed paraffin-embedded tissue samples from patients
with squamous cell carcinoma of the head and neck treated on clinical trial RTOG-9501.
OUTLINE: Formalin-fixed paraffin-embedded tissue samples are analyzed by DNA microarray
analysis for gene expression profiling.
;
Observational Model: Case-Only, Time Perspective: Retrospective
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