Conditioned Pain Modulation Using Painful Cutaneous Electrical Stimulation or Simply Habituation?

Habituation Clinical Trial

Official title:

Conditioned Pain Modulation Using Painful Cutaneous Electrical Stimulation or Simply Habituation?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03237650
• Other study ID #: PCES-Hab
• Status: Completed
• Phase: N/A
• First received: July 30, 2017
• Last updated: July 30, 2017
• Start date: April 2016
• Est. completion date: September 2016

Study information

• Verified date: July 2017
• Source: Ruhr University of Bochum
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Painful cutaneous electrical stimulation (PCES) and corresponding evoked potentials led to a significant pain relief and decrease of evoked potentials and has been used to analyze conditioned pain modulation (CPM). However, it is unknown whether the pain relief results from habituation to the repeated painful electric stimulation. We compared the effects of CPM and habituation on PCES-induced pain and PCES-evoked potentials and analyzed whether increased attention by a random change of electric intensities amplifies the habituation effects.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 33
• Est. completion date: September 2016
• Est. primary completion date: September 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• healthy volunteers

Exclusion Criteria:

• any kind of disease

Related Conditions & MeSH terms

• Habituation
• Substance-Related Disorders

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ruhr University of Bochum

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pain relief	pain intensity of painful cutaneous electrical stimulation on a numeric rating scale (NRS 0-100)	during the measurement
Primary	N1P1-amplitude	Amplitudes of painful cutaneous electrical stimulation evoked potentials in µV	during the measurement
Secondary	N1-latency	Latency of the peak N1 of painful cutaneous electrical stimulation evoked potentials in msec	during the measurement
Secondary	P0N1-amplitude	Amplitudes of painful cutaneous electrical stimulation evoked potentials in µV	during the measurement