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NCT05509244 Clinical Trial

Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Laparoscopic Gynecology Surgery

Gynecologic Disease Clinical Trial

Official title:
Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Laparoscopic Gynecology Surgery

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05509244
Other study ID # acetaminophen-ibuprofen
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date September 9, 2022
Est. completion date August 31, 2023

Study information
Verified date September 2022
Source The Catholic University of Korea
Contact youngeun moon, MD, PhD
Phone 822-2258-6163
Email 0910momo@naver.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen only and 2) acetaminophen and ibuprofen combination at postoperative pain after laparoscopic gynecologic surgery.

Description:

Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen 1g only and 2) the combination of acetaminophen 1g and ibuprofen 300mg at postoperative pain after laparoscopic gynecologic surgery. Some recovery valuables such as the postoperative pain and opioid requirements will be assessed.

Recruitment information / eligibility
Status Recruiting
Enrollment 64
Est. completion date August 31, 2023
Est. primary completion date August 24, 2023
Accepts healthy volunteers No
Gender Female
Age group 20 Years to 70 Years
Eligibility Inclusion Criteria: - Patients scheduled gynecologic laparoscopic surgery Exclusion Criteria: 1. Refusal to be enrolled in the study 2. Emergency surgery 3. On chronic pain medications 4. Psychiatric disorders 5. Pregnant, lactating women 6. Allergy or contraindication to the medication drugs

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Acetaminophen
acetaminophen 1g iv dripping at end of surgery
• Ibuprofen
ibuprofen 300mg iv dripping at end of surgery

Locations
Country Name City State
Korea, Republic of Seoul St.Mary's Hospital Seoul Seocho-gu

Sponsors (1)
Lead Sponsor Collaborator
The Catholic University of Korea

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary postoperative pain the maximal postoperative pain severity using pain scale (0=no pain; 10=the worst pain) during 30 minutes after surgery
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