GVHD Clinical Trial - Proof-of-concept Trial of Apraglutide in GVHD

Status Active, not recruiting

Clinical Trial Summary

The aim of this trial is to assess safety and efficacy of apraglutide in subjects with steroid refractory gastrointestinal acute graft versus host disease (aGVHD).

Clinical Trial Description

This is an international, multicenter, randomized proof-of-concept trial to evaluate safety, tolerability, efficacy, durability of response, and clinical outcomes of apraglutide administration to subjects with steroid-refractory (SR) aGVHD of the lower GI tract being treated with systemic steroids (SS) and ruxolitinib (RUX). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05415410
Study type	Interventional
Source	VectivBio AG
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	May 25, 2022
Completion date	August 30, 2025

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See also
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