IL-6 Regulation of Energy Stores During Recovery From an Acute Exercise Bout — REX-6

Glycogen Depletion Clinical Trial

Official title:
Role of IL-6 in Regulating Energy Stores During Recovery From an Acute Exercise Bout

Status Completed

Clinical Trial Summary

The aim of the study is to investigate the role of exercise-induced IL-6 in regulating energy stores and energy metabolism during recovery after an acute exercise bout. To achieve this, 30 men will be randomized to infusion placebo or tocilizumab (IL-6 receptor antibody) combined with a 2-hour exercise bout. Stable isotope tracers will be infused to determine substrate kinetics. Indirect calorimetry will be applied to determine substrate oxidation, and muscle biopsies will be taken to determine substrate uptake and storage.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Glycogen Depletion

Clinical Trial Details

NCT number	NCT05349149
Study type	Interventional
Source	Rigshospitalet, Denmark
Contact
Status	Completed
Phase	N/A
Start date	April 20, 2022
Completion date	October 11, 2022

View Details

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