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Dietary Fibre and Metabolic Benefits

Glucose Tolerance Clinical Trial

Official title:
Validation of a New Antidiabetic Food Concept Based on Modulation of the Gut Microbiota

Clinical Trial Summary

The aim of the project is to study the connection between bacterial fermentation in the colon of prebiotic substrates and effects on systemic metabolism and appetite i healthy humans

Clinical Trial Description

The purpose with this project is to study the association between bacterial fermentation in the colon of specific mixtures of cereal dietary fiber and effects on systemic metabolism and appetite regulation. For this purpose, short term studies are performed in healthy adult subjects. Different cereals, cereal blends and from cereal extracted dietary fiber will be studied, as well as effects of different processing of the cereals. Cardiometabolic test markers and colonic fermentation metabolites will be followed up to 14 h after intake of the test substrates, and gut microbiota composition will be determined prior to and after the interventions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03423381
Study type Interventional
Source Lund University
Contact
Status Completed
Phase N/A
Start date May 30, 2018
Completion date February 28, 2019
View Details
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