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Glomerulonephritis Acute clinical trials

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NCT ID: NCT04428398 Completed - Clinical trials for Glomerulonephritis Acute

Urinary T Lymphocytes Predict Renal Flares in Patients With Inactive ANCA-associated Glomerulonephritis

PRE-FLARED
Start date: May 1, 2020
Phase:
Study type: Observational

Urinary CD4+ and CD8+ T lymphocytes may predict renal flares in patients with inactive ANCA-associated vasculitis and thus serve as early non-invasive biomarkers. Urine samples of patients with inactive renal ANCA-vasculitis will be analysed by flow cytometry and compared to clinical outcome after 6 months.

NCT ID: NCT04320667 Active, not recruiting - Clinical trials for Glomerulonephritis Acute

Urinary T Cell Biomarker for Prediction in ANCA Glomerulonephritis

Start date: November 19, 2019
Phase:
Study type: Observational

Urinary T lymphocytes may be predictive for clinical outcome in patients with ANCA associated glomerulonephritis (ANCA GN). The investigators hypothesize that the amount of CD4+ effector/memory T cells in urine at time of diagnosis predicts the outcome of patients with active ANCA GN after 6 months of therapy. In a prospective, six-months follow-up study patients' urine will be analysed by flow cytometry every 60 days (+/- 10d). Treatment will be performed to the discretion of the treating clinician. After 6 months of treatment response will be determined as either complete response or partial response.