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Clinical Trial Summary

ATRX (X-linked mental retardation and alpha-thalassaemia syndrome protein) loss and pTERT (Telomerase reverse transcriptase) mutation are diagnostic markers of gliomas. However, 4 to 28% of gliomas shows none of these alterations. The aim of this project is to propose a new test able to detect the telomeric status for every glioma. Based on this test and other markers (such as mutation of IDH1 (isocitrate dehydrogenase 1) and IDH2 (isocitrate dehydrogenase 2)), investigators propose an algorithm, able to classify the main subtypes of gliomas (astrocytoma, oligodendroglioma and glioblastoma).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04194593
Study type Observational
Source Hospices Civils de Lyon
Contact
Status Active, not recruiting
Phase
Start date December 1, 2018
Completion date March 1, 2021

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