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A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Glioma Clinical Trial

Official title:
A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Clinical Trial Summary

To determine the efficacy of Pulse Reduced Dose Rate (PRDR) radiation when given in 27 fraction over 5.5 weeks with concurrent bevacizumab followed by adjuvant bevacizumab until time of progression in patients with recurrent high grade gliomas (grade III and grade IV). Patients will be placed in 1 of 4 groups based on their histologic diagnosis and prior exposure to bevacizumab.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01743950
Study type Interventional
Source University of Wisconsin, Madison
Contact
Status Active, not recruiting
Phase Phase 2
Start date December 3, 2012
Completion date December 2025
View Details
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