Glioma Clinical Trial
Official title:
Establishment of a Brain and Spinal Tumor Tissue Bank and Clinical Data Repository for Identifying Molecular Markers of Clinical Outcome
The purpose of this study is to establish a Brain and Spinal Tumor Tissue/Specimen repository to serve as a resource for current and future scientific studies.
Glioblastoma multiforme (GBM) is the most common and lethal primary Brain and Spinal Tumor in adults. It is nearly uniformly fatal, with a median survival of approximately one year, despite modern treatment modalities. Efforts to understand why some patients live longer or shorter than the average may provide insights into the biology of these neoplasms. For years, researchers have tried to identify independent predictors that could help in treatment planning. With the recent interest in molecular biology and molecular genetics, tumor markers are now being examined as potential predictors. A marker that could predict tumor response to therapy, the likelihood of recurrence, and survival would thus be quite useful. ;
Observational Model: Case-Only, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
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Active, not recruiting |
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N/A | |
Enrolling by invitation |
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Terminated |
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Phase 1 | |
Completed |
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Phase 2 | |
Recruiting |
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Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy
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N/A | |
Completed |
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Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed)
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Phase 2 | |
Recruiting |
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Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)
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Not yet recruiting |
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NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors
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Phase 1 | |
Completed |
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A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma
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Phase 2 | |
Terminated |
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Enhanced Detection in Glioma Excision
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N/A | |
Not yet recruiting |
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Glioma Intraoperative MicroElectroCorticoGraphy
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N/A | |
Recruiting |
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MMR/MSI Phenotypes in Prediction of Tumor Vaccine Benefit for Gliomas
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Not yet recruiting |
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N/A | |
Not yet recruiting |
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Evaluation of the Incidence of NTRK Gene Fusion in Adult Brain Tumours
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Completed |
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Phase 1 | |
Completed |
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N/A | |
Terminated |
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Phase 1 | |
Completed |
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Phase 3 | |
Completed |
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Not yet recruiting |
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Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors
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N/A |