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NCT04943107 Clinical Trial

Effect of Antihypertensive Drugs on Glaucoma Patients

Glaucoma Clinical Trial

Official title:
Effect of Antihypertensive Drugs on Glaucoma Patients

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04943107
Other study ID # 2021-0287
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date May 1, 2021
Est. completion date December 31, 2022

Study information
Verified date May 2021
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Kaijun Wang, MD
Phone +86 13600529217
Email wkj992@126.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

It has been reported that among Asian non-glaucomatous, antihypertensive medications were associated with retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness. In order to explore whether antihypertensive medications would influence the neuropathy among glaucomatous population, we designed a cross-sectional observational study to analyze the retinal status among glaucoma patients with use of antihypertensive medication.

Description:

we designed a cross-sectional obeservational study to analyze the retinal status among glaucoma patients with use of hyertensive medication.

Recruitment information / eligibility
Status Recruiting
Enrollment 200
Est. completion date December 31, 2022
Est. primary completion date December 1, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - age no less than 18 years - best corrected visual acuity better than decimal 0.3 Exclusion Criteria: - secondary glaucoma - secondary hypertension - glaucoma-related operation history - pregnancy or lactation period - uncooperative with retinal examination - severe opacity with refracting media in eye - severe retinal diseases and neuropathy - congenital retinal optic nerve abnormality - other systemic diseases that influence hypertension and glaucoma assessment

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• no intervention
no intervention, only measurement of blood pressure, intraocular pressure, hypertensive history questionnaire, retinal imaging, optical coherence tomography examination etc..

Locations
Country Name City State
China 2nd Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou Zhejiang

Sponsors (1)
Lead Sponsor Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary retinal nerve fiber layer thickness retinal nerve fiber layer thickness measured by optical coherence tomography within 3 months from recruitment
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