Glaucoma Clinical Trial
Official title:
Anterior Segment Changes Before and After Uneventful Combined Phaco-Trabeculectomy by Using Optical Coherence Tomography (OCT)
1. Develop a measurement protocol by OCT imaging and characterization of the anterior
chamber change in glaucoma patients before and after surgery.
2. Show the effect of combined surgery in control of intra ocular pressure.
Status | Recruiting |
Enrollment | 40 |
Est. completion date | March 1, 2020 |
Est. primary completion date | September 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Men and women aged over 18 years - Diagnosed primary open angle glaucoma - Visual field defects and optic nerve head appearance characteristic for glaucoma - Angle closure predisposition as evidenced from gonioscopy. - Neovascularization in the anterior chamber angle - pseudo-exfoliation glaucoma as evidenced from slit lamp examination - No cataract surgery. - No glaucoma surgery - No degenerative changes in the retina in funduscopy after mydriasis Exclusion Criteria: - -previous glaucoma surgery - Previous cataract surgery - Presence of any abnormalities preventing reliable measurements - Ocular inflammation and ocular disease interfering with the study - Corneal, macula, and other corneal disease. - No fixation Funds lesions such as diabetic retinopathy or retinal detachment. |
Country | Name | City | State |
---|---|---|---|
Egypt | Assiut university | Assiut |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Egypt,
Hong CJ, Trope GE. Glaucoma. CMAJ. 2015 Sep 8;187(12):E398-9. doi: 10.1503/cmaj.140401. Epub 2014 Nov 24. — View Citation
Maslin JS, Barkana Y, Dorairaj SK. Anterior segment imaging in glaucoma: An updated review. Indian J Ophthalmol. 2015 Aug;63(8):630-40. doi: 10.4103/0301-4738.169787. Review. — View Citation
Salim S. The role of anterior segment optical coherence tomography in glaucoma. J Ophthalmol. 2012;2012:476801. doi: 10.1155/2012/476801. Epub 2012 Aug 1. — View Citation
Sharma R, Sharma A, Arora T, Sharma S, Sobti A, Jha B, Chaturvedi N, Dada T. Application of anterior segment optical coherence tomography in glaucoma. Surv Ophthalmol. 2014 May-Jun;59(3):311-27. doi: 10.1016/j.survophthal.2013.06.005. Epub 2013 Oct 15. Re — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Biometric parameters measured with the AS-OCT (AC depth (ACD)) after surgery. - anterior chamber depth in mm | anterior chamber depth in mm Distance from corneal endothelium to anterior surface of the lens | one week post operative | |
Secondary | other biometric parameters measured with the AS-OCT, | Parameter Unit Iris thickness µT Iris curvature µC AC width µC Angle opening distance µO Angle recess area µR Trabecular iris angle Degrees Lens vault µV |
1,3,6, month postoperative | |
Secondary | intra ocular pressure | intra ocular pressure in mm hg | 1,3,6, month postoperative |
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