Glaucoma Clinical Trial
Official title:
Segmental Analysis of Retinal Layers and Measurement of Lamina Cribrosa Thickness in Patients With Asymmetric Primary Open-Angle Glaucoma
NCT number | NCT02622191 |
Other study ID # | 12-229 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | November 2012 |
Est. completion date | December 2013 |
Verified date | February 2019 |
Source | Wills Eye |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The study aims to further understand glaucoma pathogenesis and progression by utilizing enhanced depth imaging optical coherence tomography to visualize and measure lamina cribrosa in vivo and segmentation technology to accurately delineate and measure boundaries of the retinal layers. Investigators will elaborate further on key concepts of lamina cribrosa thickness and trans-synaptic degeneration.
Status | Completed |
Enrollment | 33 |
Est. completion date | December 2013 |
Est. primary completion date | February 2013 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Best-corrected visual acuity of 20/40 or better - No media opacities - Spherical equivalent refractive errors in a range of -6 to +6 diopters - Cylinder correction within 3.0 diopters. Exclusion Criteria: - Age < 18 years old - Visual Acuity < 20/40 - Nuclear sclerosis > +2 - Corneal diseases - Contact lens use - History of posterior segment intraocular surgery - Systemic or ocular diseases that can cause visual field loss. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Wills Eye |
Zangalli CS, Ahmed OM, Waisbourd M, H Ali M, Cvintal V, Affel E, Gupta L, Katz LJ, C Sergott R. Segmental Analysis of Macular Layers in Patients With Unilateral Primary Open-Angle Glaucoma. J Glaucoma. 2016 Apr;25(4):e401-7. doi: 10.1097/IJG.0000000000000 — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Lamina Cribrosa (Boundaries of the Retinal Layers) Measurements | Using Spectral Domain optical coherence tomography (SD-OCT), horizontal macular thickness of the lamina cribrosa (boundaries of the retinal layers) is measured in the eyes of each participant in microohms. | 1 examination, approximately one hour |
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