Glaucoma Clinical Trial
Official title:
The Effect of Mozart Music on Visual Field Testing in Glaucoma Patients: Will Music Tame the Savage Perimeter?
The purpose of this study is to examine if there is a difference between glaucoma patients having background music and not having background music before visual field testing.
Glaucoma is one of the leading causes of blindness in the United States. Over 2.5 million
people in the United States have glaucoma. The goal of ophthalmologists is two-fold: 1) to
detect glaucoma early, and 2) to stop the progression of disease and subsequent visual loss.
Many parameters are used to detect and follow glaucoma over the patient's lifetime including
optic nerve appearance, intraocular pressure by applanation and visual field perimetry
testing results. Perimetry testing aims to detect visual field loss that may be associated
with glaucoma and institute more aggressive treatment measures when necessary. However, it
is suspected that 50% or more of the optic nerve fibers are already irreversibly damaged
before a visual field defect can be identified on testing. Furthermore, the patient's
ability to take a visual field test is paramount in the doctor's ability to interpret the
test. That is, if a visual field test taker performs the test with low reliability (i.e. too
many false positive, false negative or fixation losses), the interpretability of the test by
the ophthalmologist is difficult or impossible.
Interestingly, a recent study in the British Journal of Ophthalmology suggested the positive
effect Mozart music has on visual field test taking ability. This study showed better first
time automated perimetry performance in normals immediately following exposure to the first
10 minutes of Mozart's Sonata for Two Pianos in D Major. The music group had 20 times fewer
fixation losses, three times fewer false positive responses and 10 times fewer false
negative responses.
No study has determined if Mozart music improves the reliability indices of Humphrey visual
field testing for glaucoma patients or experienced test takers. In efforts to improve
patient's reliability on visual field testing, we propose a randomized controlled trial to
determine if listening to music before field testing improves testing reliability.
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