Macular Pigment Optical Density in Primary Angle-closure Disease

Status Recruiting

Clinical Trial Summary

Glaucoma is the leading cause of irreversible blindness in the world, and primary angle-closure glaucoma (PACG) is the most important type of glaucoma in Asia. Primary angle closure disease (PACD) is a group of diseases related to PACG, and the pathogenesis is still unclear. Macular pigment has the functions of filtering short-wavelength waves and anti-oxidation, which are related to visual function. Previous studies have found that the macular pigment density (MPOD) is significantly reduced in primary open-angle glaucoma. This project uses the single-wavelength reflection method to measure MPOD, observes the characteristics of PACD and the normal control group's changes in retinal MPOD, and explains the relationship between PACD's MPOD changes and angle-closure glaucoma optic nerve damage

Clinical Trial Description

Observation index： Visual acuity，Intraocular pressure，Ophthalmoscope，MPOD，Visual field and OCT. Inspection parameters of OCT： 1. Retinal nerve fiber layer thickness 2. Ganglion cell complex thickness 3. Mean thickness of the central retina 4. Mean defect ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05251792
Study type	Observational
Source	Zhongshan Ophthalmic Center, Sun Yat-sen University
Contact	Zhihong Huang, M.D
Phone	+8602066615461
Email	575772588@qq.com
Status	Recruiting
Phase
Start date	November 11, 2021
Completion date	December 30, 2024

View Details

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