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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT02017327 Completed - Ocular Hypertension Clinical Trials

Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose

Start date: December 2013
Phase: Phase 4
Study type: Interventional

Primary objective: The primary objective is to demonstrate the superiority of Monoprost® versus Lumigan® 0.01% and Lumigan® 0.03% Unit Dose in term of safety with respect to the assessment of conjunctival hyperaemia in the worse eye at Day 84. The conjunctival hyperaemia will be scored using the MacMonnies photographic scale (0 to 5).

NCT ID: NCT02016898 Completed - Clinical trials for Primary Open Angle Glaucoma

The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration Device

Start date: March 2014
Phase: Phase 2
Study type: Interventional

The primary focus of this study is to assess intraocular pressure and complication rates between patients who receive mitomycin-C using a sponge versus no-sponge.

NCT ID: NCT02014597 Terminated - Glaucoma Clinical Trials

Human Optokinetic Contrast Device (HOCD) to Measure Visual Function and Identify Patients With and Without Glaucoma

HOCD
Start date: May 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if an optokinetic contrast detection device is sufficient to measure contrast sensitivity and to distinguish between patients with and without glaucoma.

NCT ID: NCT02014389 Recruiting - Glaucoma Clinical Trials

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Start date: December 1, 2013
Phase:
Study type: Observational

Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.

NCT ID: NCT02014142 Completed - Ocular Hypertension Clinical Trials

A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma

Start date: December 2013
Phase: Phase 2
Study type: Interventional

Determine efficacy of the latanoprost punctal plug. Effect of configuration of L-PPDS placement on efficacy will also be examined.

NCT ID: NCT02006693 Completed - Clinical trials for Primary Open Angle Glaucoma

Evaluation of the XEN Implant in Moderate Primary Open Angle Glaucoma (POAG) Participants

Start date: December 5, 2013
Phase: Phase 4
Study type: Interventional

The objective of this study was to evaluate the AqueSys XEN Implant [XEN® Gel Stent (XEN45 Implant)] for the treatment of moderate primary open angle glaucoma (POAG) participants when medications have failed to control intraocular pressure (IOP). Effectiveness was evaluated by comparing medicated preoperative IOP to postoperative values. Additionally, the number of topical IOP-lowering medications at screening were compared to the number of IOP-lowering medications at 1 year.

NCT ID: NCT02003547 Completed - Glaucoma Clinical Trials

A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjects

Start date: September 2013
Phase: Phase 1
Study type: Interventional

A Single Centre, Placebo-Controlled, Double-Masked, Sequential Designed Study to Evaluate 3 Ophthalmic Formulations of AMA0076 in Healthy Subjects

NCT ID: NCT02003534 Completed - Ocular Hypertension Clinical Trials

A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertension

APOTUS
Start date: July 2010
Phase: Phase 4
Study type: Interventional

This study will evaluate 0.15% brimonidine tartrate in patients with primary open angle glaucoma and ocular hypertension.

NCT ID: NCT02001155 Completed - Glaucoma Clinical Trials

Comparing the Effect of the Water Drinking Test on Intraocular Pressure

Start date: July 2013
Phase: N/A
Study type: Observational

A test that was common in the 1960's and was used to detect primary open angle glaucoma was the water drinking test (patients drank 1 quart of water to stress the fluid drainage mechanism of the eyes. Intraocular pressure was then measured over the next hour). Recently this test has been demonstrated as a predictor of peak eye pressure during the day. The purpose of this study is to compare the results of the water drinking test between eyes that have undergone trabeculectomy and eyes that have undergone tube shunt surgery.

NCT ID: NCT01999348 Completed - Ocular Hypertension Clinical Trials

A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical Setting

Start date: November 25, 2013
Phase:
Study type: Observational

The study will evaluate patients diagnosed with POAG or OHT who are switched to GANFORT® UD (unit dose of fixed combination bimatoprost and timolol) therapy for medical reasons in accordance with physician standard clinical practice. All treatment decisions lie with the physician.