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Glaucoma clinical trials

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NCT ID: NCT00487214 Completed - Clinical trials for Glaucoma, Open-Angle

Internet-based, Naturalistic Evaluation of Tolerability and Individual Patient Target Pressures With Bimatoprost 0.03% in Glaucoma

Start date: June 2002
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the range of target IOPs set for glaucoma patients starting monotherapy with bimatoprost and to evaluate patient and physician satisfaction with bimatoprost in "real-world" settings

NCT ID: NCT00486486 Completed - Glaucoma Clinical Trials

24-hour Intraocular Pressure (IOP) Control With the Bimatoprost/Timolol Fixed Combination

BTFC
Start date: March 2007
Phase: Phase 4
Study type: Interventional

The objective of this crossover, randomized, placebo controlled, double-masked study is to compare the short-term (12 weeks) mean 24-hour IOP control and safety of the new fixed combination (bimatoprost/timolol, BTFC) given PM with placebo once in the morning, versus BTFC given AM with placebo once in the evening versus bimatoprost given in the evening in patients with exfoliative glaucoma (XFG).

NCT ID: NCT00486252 Completed - Ocular Hypertension Clinical Trials

Non Interventional Study in Patients With Open Angle Glaucoma and/or Ocular Hypertension Treated With XALATAN®

Start date: June 2007
Phase:
Study type: Observational

The primary objective is to evaluate the Intraocular pressure reducing effect of Xalatan over 3 months. The secondary objective is to study the other efficacy parameters during treatment for 3 months

NCT ID: NCT00485108 Completed - Clinical trials for Primary Open Angle Glaucoma

Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty

Start date: January 2007
Phase: N/A
Study type: Interventional

The type of anti-inflammatory medication used post selective laser trabeculoplasty (SLT) may have an impact on the intra-ocular pressure (IOP) lowering effect of SLT. This study will evaluate the IOP lowering effect of SLT following the topical administration of one of the following: prednisolone 1%, ketorolac 0.5% or artificial tears.

NCT ID: NCT00481208 Completed - Open-Angle Glaucoma Clinical Trials

Diurnal Intraocular Pressure and Peripapillary Retinal Blood Flow in Medically Controlled Open-Angle Glaucoma

IOPMG
Start date: March 2006
Phase: N/A
Study type: Observational

Diurnal fluctuations of intraocular pressure (IOP) and peripapillary retinal blood flow may have distinctive patterns in medically well-controlled open-angle glaucoma patients. In the results, we found a unique pattern, 'Latent asymmetric IOP', defined as the IOP which differs between the eyes only when placed in the supine position. Unique effects of this latent asymmetric IOP on Visual field and diurnal IOP fluctuations were studied.

NCT ID: NCT00477685 Completed - Cataract Clinical Trials

Ologen (OculusGen)-Phacotrabeculectomy Historical Control Study in India

Start date: May 2007
Phase: Phase 3
Study type: Interventional

1. . Study Objective: The objective of this study is to determine the safety and effectiveness of the OculusGenTM Biodegradable Collagen Matrix Implant in phacotrabeculectomy surgery. The primary endpoint is to prove the effectiveness via the reduction of Intraocular Pressure, and the secondary endpoint is to prove the safety via the incidence of complications and adverse events. 2. . Study Design: The study is designed as a historical controlled study. Patient who meet the inclusion/exclusion criteria and sign the informed consent form will be included for this study. The allocation of subjects is non-randomized, and there is a single group for assignment. 3. . Follow-Up: This investigation is including 7 post-operative visits and follow-up within 6 months from the date of surgery. Patients should be seen at postoperative days 1, 7, 14, 30, 60, 90 and 180. The visit window of ± 7 days is allowed for the 30, 60, 90 and 180 day visits. The further follow-up of subject after trial is continually tracked by the investigator.

NCT ID: NCT00472810 Completed - Glaucoma Clinical Trials

Ologen (OculusGen)-Glaucoma MMC Control in Pakistan

Start date: March 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of the ologen (OculusGen) Biodegradable Collagen Matrix Implant and the MMC group in filtration surgery.

NCT ID: NCT00471380 Completed - Glaucoma Clinical Trials

A Phase IV Study of Travoprost + Brinzolamide to Treat Glaucoma or Ocular Hypertension

Start date: March 2007
Phase: Phase 4
Study type: Interventional

Double blind, crossover randomized, multicentric study to compare efficacy and tolerability of concomitant administration of travoprost and brinzolamide versus timolol-dorzolamide fixed combination in patients with glaucoma or ocular hypertension

NCT ID: NCT00470964 Completed - Clinical trials for Glaucoma, Open-Angle

Titanium-Sapphire Laser Trabeculoplasty in Glaucoma: A Randomized Study Comparing Titanium-Sapphire With Argon Laser Trabeculoplasty in Open-Angle Glaucoma Patients

Start date: n/a
Phase: N/A
Study type: Interventional

Titanium Sapphire laser trabeculoplasty is effective in lowering intraocular pressure in glaucoma patients, and is comparable to argon laser trabeculoplasty

NCT ID: NCT00468988 Completed - Glaucoma Clinical Trials

Short Term Comparative Study of Xalatan With Benzalkonium Chloride vs. Travatan Z Without Benzalkonium Chloride in Healthy Volunteers

Start date: May 2007
Phase: Phase 4
Study type: Interventional

Compare the effect of Xalatan with benzalkonium chloride on the ocular surface to those effects observed with Travatan Z without benzalkonium chloride after a single dose