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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT02959242 Recruiting - Glaucoma Clinical Trials

Dresden Glaucoma and Treatment Study (DGTS)

Start date: January 2006
Phase:
Study type: Observational

To assure the quality of follow-up and treatment, data of glaucoma patients are stored and evaluated after anonymisation.

NCT ID: NCT02955849 Completed - Glaucoma Clinical Trials

A Trial of China Laser and Surgery Study Glaucoma in Rural China

Start date: September 2016
Phase: Early Phase 1
Study type: Interventional

Aims and Objectives (Quantitative) Aim: To compare the effectiveness of selective laser trabeculoplasty with trabeculoplasty in lowering the intraocular pressure in patients with medically uncontrolled open angle glaucoma in rural China, taking into account the impact of patient acceptance of each type of treatment Hypothesis: Mean intraocular pressure after treatment with selective laser trabeculoplasty will be lower than with surgery due to higher acceptance rates among patients randomized to receive this treatment and therefore treatment provided at an earlier stage of disease progression.

NCT ID: NCT02955641 Recruiting - Clinical trials for Glaucoma, Angle-Closure

Efficacy and Necessity of Anti-inflammatory Drops After Laser Peripheral Iridotomy

Start date: November 1, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and need for prescribing anti-inflammatory topical drops to patients undergoing laser peripheral iridotomy.

NCT ID: NCT02947867 Not yet recruiting - Clinical trials for Neovascular Glaucoma

Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG

STRONG
Start date: January 2017
Phase: Phase 2/Phase 3
Study type: Interventional

A prospective, randomised, placebo-controlled, double-masked, three-armed multi-centre phase II/III trial for the Study of a Topical Treatment of Ischaemic Central Retinal Vein Occlusion to Prevent Neovascular Glaucoma - the STRONG Study

NCT ID: NCT02945202 Not yet recruiting - Glaucoma Clinical Trials

Influence of Trabeculectomy and Phaco-trabeculectomy on Corneal Astigmatism

Start date: January 2017
Phase: N/A
Study type: Interventional

This study investigates the effects of trabeculectomy and combined phacoemulsification plus trabeculectomy on corneal astigmatism.

NCT ID: NCT02928289 Terminated - Open-Angle Glaucoma Clinical Trials

Randomized Study of the Safety and Effectiveness of the Sight Sciences VISCO™360 Viscosurgical System Versus SLT in Primary Open Angle Glaucoma (VISCO360 Study)

Start date: January 23, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of the Sight Sciences VISCO™360 Viscosurgical System in reducing intraocular pressure (IOP) in adult, pseudophakic subjects with open-angle glaucoma.

NCT ID: NCT02921568 Recruiting - Glaucoma Clinical Trials

Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes

Start date: September 2016
Phase: N/A
Study type: Interventional

This study is designed to evaluate and compare in-tissue performance of OCT scans on the new Optos P200TE, versus the predicate Optos Spectral OCT/SLO device.

NCT ID: NCT02917564 Recruiting - Glaucoma Clinical Trials

Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery

TRICEPS
Start date: October 14, 2020
Phase: Phase 4
Study type: Interventional

During glaucoma surgery, a new opening is created that allows fluid to drain out of the eye, bypassing the clogged drainage channels that are malfunctioning in patients with glaucoma. In some patients who have had glaucoma surgery too much fluid flows out and this results in a pressure that is too low. This may cause swelling of one layer at the back of the eye called the choroid. The formation of this swelling, called a choroidal effusion or "choroidal", often makes the eye pressure stay too low, and one of the results is a decrease in vision. The treatment for a choroidal effusion is to try to raise the eye pressure somewhat to allow the swelling to subside. In our clinical work, we have found that an injection with an anti-inflammatory drug called triamcinolone appears to be helpful in speeding up healing. We plan to compare two groups of patients with choroidal effusions, one group that gets an injection of triamcinolone and one that gets a "sham" treatment with nothing injected and compare the length of time it takes the choroidal effusions to disappear. Both groups receive the standard treatment with eye drops. We will also assess the outcome of the glaucoma surgery and any other complications that may occur. This research is aimed at studying a new method of improving the outcomes of surgery for glaucoma patients, and further the treatment of glaucoma.

NCT ID: NCT02914626 Not yet recruiting - Clinical trials for Glaucoma, Neovascular

Intravitreal Ranibizumab (Lucentis®) for Neovascular Glaucoma- a Randomized Controlled Study

Start date: October 2016
Phase: Phase 3
Study type: Interventional

Neovascular glaucoma is a potentially blinding condition characterized by the growth of newvessels at the anterior part of the eye. This growth is driven by the overexpression of a protein called Vascular Endothelial Growth Factor (VEGF). That happens in diseases such as diabetic retinopathy or venous retinal occlusion, and lead to a fast increase in intraocular pressure (IOP). Traditional treatment include laser photocoagulation of the retina in order to decrease VEGF formation. The investigators postulate that the use of anti-VEGF intravitreal injections may accelerate recovery and decrease the need of surgery in cases of neovascular glaucoma.

NCT ID: NCT02914509 Completed - Ocular Hypertension Clinical Trials

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Start date: November 7, 2016
Phase: Phase 3
Study type: Interventional

The objective of the study is to evaluate evaluate the safety and IOP lowering efficacy of OTX-TP, a sustained release travoprost drug product, placed in the canaliculus of the eyelid in the treatment of subjects with open-angle glaucoma or ocular hypertension