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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT03808688 Completed - Ocular Hypertension Clinical Trials

Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting

Start date: December 27, 2018
Phase: Phase 4
Study type: Interventional

To evaluate the IOP lowering efficacy of netarsudil ophthalmic solution 0.02% when used as monotherapy or when used concomitantly with other IOP-lowering agents in subjects with elevated IOP due to open angle glaucoma or ocular hypertension in a real-world clinical setting. The study is an open-label design. The patients will receive treatment for 12 weeks.

NCT ID: NCT03807869 Completed - Glaucoma Clinical Trials

Reduction of Intraocular Pressure After I-stent By-pass Implantation in Eyes With Open Angle Glaucoma

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Purpose of this study is to exam the hypotensive effectiveness of I-stent implantation depended on number of antiglaucoma eye drops at baseline.

NCT ID: NCT03804684 Completed - Clinical trials for Glaucoma, Open-Angle

visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated Perimetry

Start date: January 8, 2019
Phase: N/A
Study type: Interventional

To determine age-adjusted reference values of the visuALL Field Analyzer (vFA) retinal sensitivity and to assess the repeatability of the measured values and compare them with those measured by a Standard Automatic Perimetry (SAP).

NCT ID: NCT03800589 Completed - Clinical trials for Glaucoma, Open-Angle

Assessment of Effectiveness Ex-Press Surgery Modification

Start date: December 1, 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to compare the effectiveness and safety profile of ExPress implantation versus partial deep sclerectomy combined with ExPress implantation with simultaneously phacoemulsification.

NCT ID: NCT03798223 Active, not recruiting - Ocular Hypertension Clinical Trials

Optimal Treatment Protocol for Selective Laser Trabeculoplasty

OSLT
Start date: January 10, 2019
Phase: N/A
Study type: Interventional

A randomized controlled trial to evaluate which treatment protocol in selective laser trabeculoplasty that is most optimal in terms of efficacy and safety.

NCT ID: NCT03798145 Withdrawn - Glaucoma Clinical Trials

Surgical Retinotomy for the Treatment of Glaucoma

Start date: December 2021
Phase: N/A
Study type: Interventional

Glaucoma is a leading cause of blindness worldwide. It is caused by persistently elevated intraocular pressure causing progressive visual field loss. While a number of conventional medical and surgical therapies exist, a significant number of patients fail to respond resulting in persistently elevated intraocular pressure and eventual blindness. While outflow from the eye primarily occurs through the front of the eye, there is an often overlooked pathway to remove fluid that is beneath the retina. Surgical removal of retina to create paths for outflow (surgical retinotomy) in areas damaged by glaucoma can provide access to this alternative outflow pathway thereby reducing intraocular pressure and halting the vision loss.

NCT ID: NCT03797846 Completed - Glaucoma Clinical Trials

Comparison of Fixation Suture Type in Glaucoma Surgery

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effectiveness and safety of two types of intraoperative eye fixation: for the superior rectus muscle and traction suture in the peripheral cornea. This is a prospective randomized trial with a 6 month follow-up period, which covers patients with open angle glaucoma qualified for combined glaucoma procedure (phacotrabeculectomy). In I group, the intraoperatively fixation in the peripheral part of the cornea is used, in II group the bridle suture for the superior rectus muscle is performed.

NCT ID: NCT03797469 Completed - Clinical trials for Glaucoma, Open-Angle

Nutritional Supplements and Performance During Visual Field Testing (B3 Vitamin)

Start date: April 15, 2019
Phase: N/A
Study type: Interventional

This study seeks to test whether these over-the-counter nutritional supplements have an impact on patients' performance during visual field testing.

NCT ID: NCT03782051 Completed - Clinical trials for Primary Open-angle Glaucoma

Combined Viscocanalostomy, Phacoemulsification, OIogen Implant in Open Angle Glaucoma

Visco-ologen
Start date: August 1, 2013
Phase: N/A
Study type: Interventional

This prospective, interventional, randomized clinical study was done at Alpha Vision Center, Zagazig, Egypt. Patients with coexisting cataract and glaucoma were randomized to receive either phaco-viscocanalostomy (Phacovisco group) or phaco-viscocanalostomy with Ologen® implant (OloPhacovisco group) . Follow-up period was 2 years. Nd:YAG laser goniopuncture was done in cases where the intraocular pressure (IOP) was elevated above 21 mmHg after discontinuation of corticosteroid eye drops at any follow-up visit. Our hypothesis is that using Ologen® implant as a spacer in the subscleral reservoir in phaco-viscocanalostomy reduces fibrosis and increase the success rate of this operation

NCT ID: NCT03766425 Completed - Eye Diseases Clinical Trials

Comparison of Efficacy and Safety of Mitomycin and Aflibercept Used to Support Primary Trabeculectomy.

Start date: June 14, 2017
Phase: Early Phase 1
Study type: Interventional

Comparison of efficacy and safety of Mitomycin and Aflibercept used to support primary trabeculectomy - a prospective, randomized trial in patients with open-angle glaucoma undergoing surgery.