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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT02993445 Completed - Ocular Hypertension Clinical Trials

Effect of Alternate Therapies on Intraocular Pressure in Ocular Hypertension

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of complementary and alternative therapies, specifically alternate nostril breathing and foot reflexology, on intraocular pressure in patients with ocular hypertension.

NCT ID: NCT02982629 Completed - Glaucoma Clinical Trials

Improving Access to Eye Care in Glaucoma Patients

Start date: March 2013
Phase: N/A
Study type: Interventional

1. To design and develop a prospective, randomized pilot study utilizing information from electronic medical records to address follow-up adherence and reduce the gap between recommended and actual follow-up adherence in patients with glaucoma. 2. To evaluate the impact of a telephone-based intervention on follow-up adherence in patients with glaucoma using a randomly assigned comparison with usual care.

NCT ID: NCT02981446 Completed - Clinical trials for Open Angle Glaucoma or Ocular Hypertension

A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT

Start date: January 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the intraocular pressure-lowering effect and the safety of DE-117 ophthalmic solution compared with Latanoprost ophthalmic solution in subjects with open angle glaucoma or ocular hypertension.

NCT ID: NCT02972749 Completed - Clinical trials for Intraocular Pressure

Modifiable Factors and Glaucoma - RCT

Start date: November 2016
Phase: N/A
Study type: Interventional

There is growing awareness that environmental factors, behaviors and diet are intimately related to patient health and may play a role in the pathogenesis and progression of glaucoma. Evidence from recent years has shown that some behaviors and environmental factors can affect the intraocular pressure, the primary risk factor for glaucoma. This study aims to investigate whether simple and common lifestyle inteventions such as sleeping with a head elevation, a high fiber diet, moderate aerobic exercise and moderation in caffeine intake could affect intraocular pressure and other outcomes.

NCT ID: NCT02967614 Completed - Glaucoma Clinical Trials

KJ-TFC-004 Drug-drug Interaction Study

Start date: December 2016
Phase: Phase 1
Study type: Interventional

To assess the pharmacokinetic Interaction between Dorzolamide and Brimonidine in healthy male subjects.

NCT ID: NCT02966678 Completed - Glaucoma Clinical Trials

Incidence of Dyschromatopsia in Glaucoma

Start date: November 8, 2016
Phase: N/A
Study type: Observational

Incidence of dyschromatopsia

NCT ID: NCT02959593 Completed - Clinical trials for Primary Open Angle Glaucoma

The Effects of Visior on Ocular Hemodynamics

Start date: January 2017
Phase: N/A
Study type: Interventional

To determine the relationship between the affects of viewing commercially available content through the VISIOR video goggles and ocular blood flow in glaucoma patients and healthy subjects.

NCT ID: NCT02955849 Completed - Glaucoma Clinical Trials

A Trial of China Laser and Surgery Study Glaucoma in Rural China

Start date: September 2016
Phase: Early Phase 1
Study type: Interventional

Aims and Objectives (Quantitative) Aim: To compare the effectiveness of selective laser trabeculoplasty with trabeculoplasty in lowering the intraocular pressure in patients with medically uncontrolled open angle glaucoma in rural China, taking into account the impact of patient acceptance of each type of treatment Hypothesis: Mean intraocular pressure after treatment with selective laser trabeculoplasty will be lower than with surgery due to higher acceptance rates among patients randomized to receive this treatment and therefore treatment provided at an earlier stage of disease progression.

NCT ID: NCT02914509 Completed - Ocular Hypertension Clinical Trials

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Start date: November 7, 2016
Phase: Phase 3
Study type: Interventional

The objective of the study is to evaluate evaluate the safety and IOP lowering efficacy of OTX-TP, a sustained release travoprost drug product, placed in the canaliculus of the eyelid in the treatment of subjects with open-angle glaucoma or ocular hypertension

NCT ID: NCT02901236 Completed - Glaucoma Clinical Trials

Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled Glaucoma

AvastinvsMMC
Start date: January 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Refractory glaucoma often requires vision-sparing trabeculectomy. To increase surgical success, adjunctive pharmacotherapy is utilized albeit the risk of adverse events. This prospective trial randomizes adults with uncontrolled glaucoma to assess an emerging healing modulatory strategy. Over a 1-year follow-up, trabeculectomy complemented with intracameral delivery of anti-angiogenic bevacizumab (1.25 mg) is compared to standard trabeculectomy with anti-fibrotic mitomycin-C (0.02%; applied for 2 minutes).