Clinical Trials Logo

Glaucoma clinical trials

View clinical trials related to Glaucoma.

Filter by:

NCT ID: NCT00856622 Completed - Glaucoma Clinical Trials

A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients

Start date: August 1997
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate that fixed combination of latanoprost and timolol (PhXA41) has better IOP lowering effect than the individual monotherapies.

NCT ID: NCT00855517 Withdrawn - Glaucoma Clinical Trials

A Phase 2 Study of the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Start date: March 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate IOP response to experimental dose of Latanoprost- PPDS in subjects with ocular hypertension or open-angle glaucoma.

NCT ID: NCT00854256 Recruiting - Glaucoma Clinical Trials

Trabeculectomy Versus Canaloplasty to Treat Glaucoma

Start date: April 2009
Phase: N/A
Study type: Interventional

The aim of the study is to investigate pressure lowering effect of two surgical methods canaloplasty and trabeculectomy in patients with open angle glaucoma, in which under local pressure lowering therapy the progression of the disease could not be stopped, and thus a pressure lowering surgical intervention is necessary. The risks in the postoperative course in Canaloplasty in the literature as lower than for the trabeculectomy with mitomycin-C. Conversely, large glaucoma centers questioning the effectiveness of permanent pressure lowering of canaloplasty. Precisely this question is investigated in the study.

NCT ID: NCT00853905 Completed - Glaucoma Clinical Trials

Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery?

Start date: February 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators hypothesize that intracameral Triesence during glaucoma surgery will provide lower intraocular pressure through better control of ocular inflammation, thus leading to a more successful filtering procedure.

NCT ID: NCT00853073 Completed - Glaucoma Clinical Trials

Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?

Avastin
Start date: February 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to see if a new add on (or adjunctive) therapy used in glaucoma surgery improves the success of needle bleb revisions.

NCT ID: NCT00848536 Completed - Ocular Hypertension Clinical Trials

Efficacy Study of Travoprost APS Versus TRAVATAN

Start date: March 2009
Phase: Phase 3
Study type: Interventional

A Multi-Center Double-masked Study of the Safety and Efficacy of Travoprost APS Compared to TRAVATAN in Patients with Open-angle Glaucoma or Ocular Hypertension

NCT ID: NCT00847483 Completed - Glaucoma Clinical Trials

Comparison of Latanoprost With Travoprost and Bimatoprost in Patients With Elevated IOP. A 12-weeks, Masked Evaluator, Phase IV Multi-center Study in the US

XLT
Start date: January 2002
Phase: Phase 4
Study type: Interventional

Compare the IOP lowering properties of latanoprost, travoprost and bimatoprost

NCT ID: NCT00846989 Completed - Glaucoma Clinical Trials

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

Start date: January 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This purpose of this study is to access the efficacy, tolerability and safety of RKI983 (0.05% and 0.10%) ophthalmic solution bid versus once daily latanoprost 0.005%, in patients with POAG or ocular hypertension.

NCT ID: NCT00845299 Completed - Glaucoma Clinical Trials

Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Start date: January 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effect of artificial tears preserved with Benzalkonium Chloride (AT-BAK) on the IOP response to the L-PPDS and to evaluate the safety of the L-PPDS in subjects with OH or OAG following treatment.

NCT ID: NCT00838721 Completed - Ocular Hypertension Clinical Trials

Evaluation of Pascal Laser Trabeculoplaty

PLT
Start date: March 2008
Phase: N/A
Study type: Interventional

Laser Trabeculoplasty has been shown to be effective in lowering intraocular pressure (IOP) in patients with primary open-angle glaucoma (POAG). Although initially demonstrated with the Argon laser (ALT), several other laser systems have also been employed with comparable efficacy. Recently, Selective Laser Trabeculoplasty (SLT) has been shown to lower intraocular pressure comparable to ALT. The advantage of SLT is that the target eye structure, the trabecular meshwork, remains intact with minimal damage at the cellular level. In contrast, ALT lowers IOP at the expense of scarring of the trabecular meshwork. The purpose of this study is to evaluate the efficacy of lowering IOP with Pascal Laser Trabeculoplasty (PLT) employing reduced energy levels compared to ALT and a computer guided pattern of laser treatment applications.