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Glaucoma clinical trials

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NCT ID: NCT00956462 Unknown status - Glaucoma Clinical Trials

Steroids Versus Non-steroidal Anti-inflammatory Drugs Following Glaucoma Surgery

Start date: July 2007
Phase: N/A
Study type: Interventional

This study aims to evaluate the eye pressure response to non-steroidal anti-inflammatory eye drops as compared to steroid eye drops following glaucoma surgery.

NCT ID: NCT00950690 Completed - Glaucoma Clinical Trials

Efficacy and Tolerability of Xalatan in Patients

A6111128
Start date: July 2005
Phase:
Study type: Observational

Efficacy data was not collected or analyzed. This study did assess safety and tolerability of Xalatan.

NCT ID: NCT00947869 Recruiting - Clinical trials for Primary Open Angle Glaucoma

Contrast Sensitivity in Glaucoma

Start date: April 2009
Phase: N/A
Study type: Observational

The primary aim of the Erlangen´s Glaucoma Contrast Sensitivity-Study (EGCS-Study) is the evaluation of the diagnostic and prognostic validity of a diagnostic procedure, measuring contrast sensitivity. No therapeutic studies are performed.

NCT ID: NCT00947661 Completed - Ocular Hypertension Clinical Trials

Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension

Start date: July 2010
Phase: Phase 3
Study type: Interventional

A single-blind , 12-week, parallel group clinical study is planned to evaluate the efficacy and safety of SPARC0912 and Reference0912. SPARC0912 is an experimental drug having similar active ingredient but containing a different preservative as that in Reference0912. Patients with open angle glaucoma or ocular hypertension will be enrolled and randomly assigned to receive either product. One drop will be instilled to the study eye nightly at 8:00 PM.

NCT ID: NCT00945958 Completed - Ocular Hypertension Clinical Trials

Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension

Start date: November 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of SPARC0913. A multicenter, open label, non-randomized, uncontrolled, single group assignment, safety study of subjects with primary open angle glaucoma or ocular hypertension is planned. Subjects will receive study medication for a period of 24-weeks.

NCT ID: NCT00941096 Completed - Glaucoma Clinical Trials

Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination

Start date: July 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to examine the ocular hypotensive effect of Bimatoprost and the potential additional effect of the Bimatoprost/Timolol fixed combination in eyes with ocular hypertension, primary open angle glaucoma or exfoliation glaucoma.

NCT ID: NCT00940823 Completed - Glaucoma Clinical Trials

The AVB Study: Prospective Study Comparing the Ahmed Valve and the Baerveldt Implant for Treating Refractory Glaucoma

Start date: July 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of the Ahmed valve and the Baerveldt implant in treating refractory glaucoma. Eligible patients will be recruited from multiple study centers and randomized to a glaucoma drainage device for implantation. They will be followed long-term based upon outcome measures including intraocular pressure, glaucoma medication use, visual acuity, complications of the surgery and further treatments required.

NCT ID: NCT00928590 Completed - Ocular Hypertension Clinical Trials

Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension

Start date: July 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to describe the long-term safety of a fixed combination product containing an alternative preservative, dosed once daily for 12 months, in patients with open-angle glaucoma or ocular hypertension.

NCT ID: NCT00918346 Completed - Ocular Hypertension Clinical Trials

Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation

Start date: September 2005
Phase: Phase 3
Study type: Interventional

The objective of this study is to investigate the pharmacodynamics (as expressed in intraocular pressure [IOP]) of two formulations of tafluprost 0.0015% eyedrops (preserved and unpreserved) in patients with open-angle glaucoma or ocular hypertension. The primary aim of this study is to show that IOP reduction between the two formulations is equivalent at the end of the 4 week treatment period.

NCT ID: NCT00917670 Completed - Uveitis Clinical Trials

Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma

Start date: May 2009
Phase: N/A
Study type: Observational

Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma. To evaluate morphological changes and to compare to primary open angle glaucoma patients.