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Glaucoma clinical trials

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NCT ID: NCT01462526 Completed - Glaucoma Clinical Trials

The Detection of Glaucoma Using Pupillography

RAPiD
Start date: March 2011
Phase: N/A
Study type: Observational

Current screening methods for glaucoma detection are not perfect and nearly half of those in the United States with glaucoma go undiagnosed. Minority populations are even less likely to be diagnosed. Better screening methods are needed to identify the undiagnosed and to provide them care that can help them retain good vision. Glaucoma is often more severe in one eye and this fact can be exploited in screening tests. The investigators plan to use a novel screening device that very accurately records the pupillary response from each eye. It is likely that patients with glaucoma will have abnormal responses when measured, and by comparing responses between the two eyes the investigators will be able to determine who has glaucoma. If this test works well, it will provide a low-cost way to screen populations at risk for glaucoma. Furthermore, this research will expand the knowledge base regarding how pupil responses to light differ between persons with and without glaucoma. Insights gained from this study will be useful in the development of an effective screening tool in the detection of glaucoma.

NCT ID: NCT01461291 Completed - Clinical trials for Primary Open-angle Glaucoma

Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract Surgery

Start date: January 16, 2012
Phase: N/A
Study type: Interventional

Evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 using the G2-M-IS injector system in conjunction with cataract surgery vs. cataract surgery only, in subjects with mild to moderate primary open-angle glaucoma.

NCT ID: NCT01461278 Completed - Clinical trials for Primary Open-angle Glaucoma

Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery

Start date: December 22, 2011
Phase: N/A
Study type: Interventional

Evaluate the safety and efficacy of the Glaukos® Suprachoroidal Stent Model G3 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate primary open-angle glaucoma.

NCT ID: NCT01460017 Unknown status - Congenital Glaucoma Clinical Trials

Comparison Between Deep Sclerectomy and Traditional Trabeculotomy & Trabeculectomy in Congenital Glaucoma

Start date: November 2011
Phase: Phase 1
Study type: Interventional

The investigators hypothesize that deep sclerectomy in congenital glaucoma is a safer procedure and may yield better results than trabeculotomy trabeculectomy approach.

NCT ID: NCT01456390 Completed - Open-Angle Glaucoma Clinical Trials

Open-Angle Glaucoma Subjects With One Prior Trabeculectomy Treated Concurrently With One Suprachoroidal Stent and Two Trabecular Micro-bypass Stents

Start date: September 2011
Phase: N/A
Study type: Interventional

Evaluation in the eyes of subjects with one prior trabeculectomy on one to three ocular hypotensive medications of the intraocular pressure (IOP) lowering effect of two iStent stents in combination with one iStent supra stent and a postoperative prostaglandin.

NCT ID: NCT01455467 Completed - Open-angle Glaucoma Clinical Trials

Open-angle Glaucoma Subjects on One Topical Hypotensive Medication Randomized to Treatment With One or Two Trabecular Micro-bypass Stents in Conjunction With Cataract Surgery

Start date: September 2011
Phase: N/A
Study type: Interventional

Evaluation of intraocular pressure (IOP) lowering effect of one iStent versus two iStents in conjunction with cataract surgery in subjects with primary open-angle glaucoma, washed out of one anti-glaucoma medication prior to stent implantation.

NCT ID: NCT01453855 Completed - Ocular Hypertension Clinical Trials

Travoprost 3-Month Safety and Efficacy Study

Start date: November 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study was to demonstrate that the intraocular pressure-lowering efficacy of Travoprost 0.003% is equivalent to TRAVATAN® in adult patients with open-angle glaucoma or ocular hypertension.

NCT ID: NCT01448837 Completed - Glaucoma Clinical Trials

24-Hour Intraocular Pressure Control With Bimatoprost/Timolol Versus Latanoprost as First Choice

Start date: April 2010
Phase: Phase 4
Study type: Interventional

The primary objective of this crossover 24-hour Intraocular Pressure (IOP) trial is to compare the control obtained after 3 months of therapy with the bimatoprost/timolol fixed combination (BTFC, Ganfort) given once in the evening (20:00) versus latanoprost (Xalatan) administered once in the evening (20:00) in newly-diagnosed patients with exfoliation syndrome (XFS) and ocular hypertension, or exfoliative glaucoma (XFG) previously untreated and IOP greater than 29 mm Hg.

NCT ID: NCT01446497 Recruiting - Clinical trials for Normal Tension Glaucoma

Efficacy and Safety Study of Combigan and 0.5% Timoptic in Normal Tension Glaucoma

Start date: October 2010
Phase: Phase 4
Study type: Interventional

Purpose To evaluate efficacy and safety of combigan(Brimonidine/Timolol) and 0.5% Timoptic (Timolol) ophthalmic solutions in normal tension glaucoma patients.

NCT ID: NCT01444105 Completed - Open-angle Glaucoma Clinical Trials

Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty

Start date: September 2011
Phase: N/A
Study type: Interventional

Evaluation of intraocular pressure (IOP) lowering effect of two iStent stents versus a SLT procedure in subjects with open-angle glaucoma on one ocular hypotensive medication.