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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT01667861 Completed - Glaucoma Clinical Trials

Risk Factors for Glaucoma in Musicians

Start date: October 2011
Phase: N/A
Study type: Observational

The purpose of this study is to determine the impact of playing wind instruments for the development of ocular hypertension and glaucoma, together with investigating the prevalence of visual problems and eye diseases in (professional) musicians.

NCT ID: NCT01664039 Completed - Glaucoma Clinical Trials

An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN®

Start date: September 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is evaluate effects of TRAVATAN® versus LUMIGAN® on intraocular pressure (IOP) and ocular surface and inflammatory biomarkers.

NCT ID: NCT01658839 Completed - Glaucoma Clinical Trials

Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients

Start date: January 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study was to assess the safety and describe the steady-state plasma pharmacokinetic (PK) profiles of Travoprost ophthalmic solution, 0.004% (new formulation) following a once daily administration for 7 days in pediatric glaucoma or ocular hypertension patients.

NCT ID: NCT01654484 Completed - Clinical trials for Glaucoma and Ocular Hypertension

A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT

Start date: July 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of up to three concentrations of DE-117 ophthalmic solution (Low Dose, Medium Dose, and High Dose) as monotherapy and as adjunctive therapy (DE-117 ophthalmic solution with 0.0015% tafluprost) in subjects with primary open-angle glaucoma or ocular hypertension.

NCT ID: NCT01652664 Completed - Pediatric Glaucoma Clinical Trials

Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients

Start date: September 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the intraocular pressure (IOP)-lowering efficacy of Travoprost 0.004% POLYQUAD (PQ) ophthalmic solution compared to Timolol ophthalmic solution (0.5% or 0.25%) in pediatric glaucoma patients.

NCT ID: NCT01646151 Completed - Ocular Hypertension Clinical Trials

A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Start date: May 2012
Phase: N/A
Study type: Observational

An observational study comparing changing from an IOP-lowering treatment to a bimatoprost-containing IOP treatment in primary open-angle glaucoma (POAG) or ocular hypertension (OHT). Visits and treatment are per normal clinical practice.

NCT ID: NCT01645319 Completed - Open Angle Glaucoma Clinical Trials

Comparative Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma

RiGOR
Start date: February 2011
Phase: N/A
Study type: Observational [Patient Registry]

The primary objectives of the study are: 1. To compare the proportion of patients who achieve a successful response to treatment (reduction in Intraocular Pressure (IOP) of >15%) between patients treated with laser surgery (including argon laser trabeculectomy, and selective laser trabeculoplasty) with patients receiving additional medications, at 1-year post-treatment initiation. 2. To compare the proportion of patients who achieve a successful response to treatment (reduction in IOP of >15%) between patients treated with other procedures (including incisional surgery, drainage device procedures, and other glaucoma procedures) with patients receiving additional medications, at 1-year-post-treatment initiation. The study is a prospective, observational cohort study and will not provide or recommend any treatment. Patients who have failed initial medical therapy with two glaucoma medications will be identified and enrolled at the time of scheduling of a laser surgery procedure or other procedure such as incisional surgery or drainage device, or initiation of an additional course of therapy with medication as determined by their physician. This inception cohort of new initiators of laser surgical treatment, other procedures, or additional medical therapy will be followed for 12 months. All decisions regarding treatment are solely at the discretion of the physician in accordance with their usual practice. Enrollment is expected to begin in February 2011 and continue through 12 months of follow-up after enrollment targets have been reached.

NCT ID: NCT01641835 Completed - Glaucoma. Clinical Trials

Optical Coherence Tomography (OCT) Data Collection Study

Start date: July 2012
Phase: N/A
Study type: Observational

Collect OCT data to evaluate the range and age trend of ocular measurements.

NCT ID: NCT01640756 Completed - Glaucoma Clinical Trials

AqueSys Microfistula Implant in Refractory Glaucoma

Start date: July 2012
Phase: Phase 3
Study type: Interventional

To establish the safety and performance of the AqueSys Microfistula Implant in eyes with refractory glaucoma.

NCT ID: NCT01639807 Recruiting - Glaucoma Clinical Trials

Clinical Evaluation of Efficacy of SLT to Topical Medication in Lowering IOP

Start date: October 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to compare Selective laser trabeculoplasty (SLT) and topical medications for initial treatment of open-angle glaucoma /Ocular Hypertension based on intraocular pressure reduction, treatment side effects, quality of life measures and costs in South Indian Population.