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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT00159653 Completed - Ocular Hypertension Clinical Trials

A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma

Start date: July 2005
Phase: Phase 3
Study type: Interventional

To demonstrate statistical superiority of the combination of latanoprost and timolol to the individual therapy of latanoprost and timolol based on intraocular pressure measurements at 8 AM, 10 AM, 4 PM at weeks 2, 6 and 12.

NCT ID: NCT00150267 Completed - Ocular Hypertension Clinical Trials

A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertension

Start date: February 2002
Phase: Phase 3
Study type: Interventional

To estimate the frequency of patients with ocular/periorbital adverse events. To identify any possible long-term adverse consequences of increased iris pigmentation and to follow serious adverse events throughout the study period.

NCT ID: NCT00145535 Completed - Glaucoma Clinical Trials

SOLX Titanium Sapphire Laser for Trabeculoplasty

Start date: May 2004
Phase: Phase 3
Study type: Interventional

Use of the Titanium Sapphire laser for laser trabeculoplasty to reduce intraocular pressure in patients with poorly controlled intraocular pressure on maximally tolerated medical therapy or prior failed laser trabeculoplasty.

NCT ID: NCT00143208 Completed - Glaucoma Clinical Trials

Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh.

Start date: May 2003
Phase: Phase 4
Study type: Interventional

This study is designed as an open label evaluation of the efficacy of latanoprost and timolol fixed combination (Xalacom) after 6 month of treatment. Eligible patients may be enrolled at the baseline visit. All current ocular hypotensive therapy must be discontinued at this time. On baseline day, patients eligible for the study will receive Xalacom which is to be instilled in the morning.

NCT ID: NCT00141882 Completed - Open-Angle Glaucoma Clinical Trials

Memantine in Patients With Chronic Glaucoma

Start date: March 1999
Phase: Phase 3
Study type: Interventional

Randomized double-masked clinical trial of memantine in patients with glaucoma

NCT ID: NCT00140062 Completed - Ocular Hypertension Clinical Trials

Efficacy And Safety Of Xalatan Compared To Usual Care In Patients With Open Angle Glaucoma Or Ocular Hypertension.

Start date: February 2002
Phase: Phase 4
Study type: Interventional

The primary purpose is to compare the intraocular pressure reducing effect of Xalatan with that of usual care over 36 months. Safety and health care utilization will be evaluated.

NCT ID: NCT00140049 Completed - Ocular Hypertension Clinical Trials

A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma

Start date: July 2005
Phase: Phase 4
Study type: Interventional

To demonstrate the statistical non inferiority of the combination of latanoprost and timolol given in the evening time once a day vs the combination of dorzamalide and timolol twice a day based on intraocular pressure measurements at 8 AM, 12 noon & 4 PM during a 12 week treatment.

NCT ID: NCT00108017 Completed - Glaucoma Clinical Trials

Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED)

Start date: April 2005
Phase: Phase 3
Study type: Interventional

This study is comparing 2 medications for glaucoma and how effective they are at controlling glaucoma over the course of an entire day.

NCT ID: NCT00069719 Completed - Ocular Hypertension Clinical Trials

Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients

Start date: February 1999
Phase: Phase 2
Study type: Interventional

To determine the safety and IOP-lowering ability of a test compound in patients with open-angle glaucoma or ocular hypertension.

NCT ID: NCT00069706 Completed - Ocular Hypertension Clinical Trials

Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patients

Start date: July 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and IOP-lowering ability of a glaucoma therapy in patients with open-angle glaucoma or ocular hypertension.