The Effect of Different Gingival Biotypes on Dimensional Stability of Free Gingival Graft

Gingival Recession Clinical Trial

Official title:

The Effect Of Different Gingival Biotypes On Dimensional Stability Of Free Gingival Graft: A Comparative 6 Month Clinical Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03616197
• Other study ID #: 2016-9/7
• Status: Completed
• Phase: N/A
• Start date: August 2016
• Est. completion date: July 2018

Study information

• Verified date: August 2018
• Source: Istanbul Aydin University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to compare the effect of mesial and distal adjacent gingival biotypes of the tooth / teeth region of free gingival graft (FGG) on the shrinkage ratio of graft at 6 months postoperatively.

Description:

The concept of gingival and periodontal phenotype was established as a result of clinical observation of changes in facial keratinized tissue width and thickness .It has been reported that gingival or periodontal diseases may develop more frequently in patients with thin gingival biotypes and that thick-flat biotype in implant restorations is important in achieving a successful aesthetic treatment outcome.

Free gingival graft (FGG) is a mucogingival surgical procedure that is successfully used in the presence of inadequate keratinized gingival width and gingival recession. It is thought that factors that may adversely affect the continuity of graft nutrition may be effective in graft shrinkage. These reasons can be listed as follows; graft thickness, traumatic surgical procedure, graft dehydration, and suturing procedure.

There was no study investigating the effect of periodontal biotypes on graft contraction in the region adjacent to the FGG operation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: July 2018
• Est. primary completion date: April 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• In the mandibular incisor tooth / teeth, the attached keratinized gingival width is <1 mm,

• No periodontal surgery has been performed previously on the involved tooth.

• In the absence of any systemic condition or illness (pregnancy, breastfeeding, mental retardation, diabetes, etc.) that may interfere with the patient's approval and dental treatment.

• Do not use any of the drug groups that may cause gingival overgrowth.

Exclusion Criteria:

• Previous periodontal surgery in the operation area

• Restoration of the buccal surface of the tooth and no pathology in the apical region of the tooth.

• In the presence of any systemic condition or illness (pregnancy, breastfeeding, mental retardation, diabetes, etc.) that may interfere with the patient's approval and dental treatment.

Related Conditions & MeSH terms

• Atrophy
• Gingival Recession

Intervention

Procedure:
• free gingival graft
A horizontal incision was made along the mucogingival line with a scalpel number 15 to prepare a bed of periosteum and a thin immobilized connective tissue. The moving gingival tissues were removed coronally, and the bed was prepared so that the immobilized keratinized gingival tissue was preserved and the graft was placed apically. The template of the recipient region was placed in the donor region to be 2-3 mm more apically than the gingival margins of the teeth. The number of 15 scalpel was used to make incision at the template border and perpendicular to the keratinized tissue. The graft thickness was standardized in all patients between 1.5-2 mm. FGG was placed over the recipient bed and 5/0 non-resorbable monofilament sutures were used for fixing the four corners of the graft.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul Aydin University

References & Publications (3)

Barbosa FI, Corrêa DS, Zenóbio EG, Costa FO, Shibli JA. Dimensional changes between free gingival grafts fixed with ethyl cyanoacrylate and silk sutures. J Int Acad Periodontol. 2009 Apr;11(2):170-6. — View Citation

Gümüs P, Buduneli E. Graft stabilization with cyanoacrylate decreases shrinkage of free gingival grafts. Aust Dent J. 2014 Mar;59(1):57-64. doi: 10.1111/adj.12149. Epub 2014 Feb 4. — View Citation

Hatipoglu H, Keçeli HG, Güncü GN, Sengün D, Tözüm TF. Vertical and horizontal dimensional evaluation of free gingival grafts in the anterior mandible: a case report series. Clin Oral Investig. 2007 Jun;11(2):107-13. Epub 2007 Feb 9. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The graft shrinkage ratio	Graft shrinkage = Preoperative area - Postoperative area X 100 Preoperative area	baseline - 6th months postoperatively
Secondary	keratinized ginigival width	Keratinized Gingival Width(KGW) was measured using a lugol solution (10% potassium iodide and 5% iodine) with a manual caliper spaced 0.5 mm from the mid-buccal point of the tooth, the distance between the gingival margin and mucogingival junction from MTT, DTT and the teeth/tooth in operation area.	baseline - 6th months postoperatively