Clinical Trials Logo
  1. Home
  2. Gingival Recession, Localized
  3. NCT05916716

Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially Restored

Gingival Recession, Localized Clinical Trial

Official title:
Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially Restored. A Randomized Clinical Trial

Clinical Trial Summary

Gingival recessions (GR) are often associated with non-carious cervical lesions (NCCL), resulting, thus, in a combined defect. This mucogingival condition has a different treatment prognosis when compared with a GR without wearing surface associated and frequently requires a surgical-restorative approach to achieve better esthetics and functional results. A limited number of clinical studies assessed different multidisciplinary protocols for the management of single combined defects and there is evidence that the use of dental materials does not harm the periodontal tissues and does not influence the root coverage obtained by means of subepithelial connective tissue graft (CTG). Although the association between coronally advanced flap (CAF) and CTG provides more predictable and stable outcomes in the long term, its use is related to some drawbacks. Different biomaterials have been developed to overcome these limitations as a possible alternative to autogenous graft. However, despite its potential, there is a lack of studies evaluating its use in treating this type of condition. Thus, this study aims to assess from a clinical and esthetics point of view and patient-centered outcomes, the use of a new collagen matrix (Geistlich Fibro-Gide®) associated with CAF for the management of single combined defects. For such purpose, 50 patients with single RT1 gingival recessions associated with NCCL will be enrolled and randomly allocated to one of the following groups: control group (n=25), partial restoration of cervical lesion and coronally advanced flap for root coverage (PR+CAF) and test group (n=25), partial restoration of cervical lesion and coronally advanced flap associated with volume stable collagen matrix (PR+CAF+VCMX). The two groups will be compared regarding the clinical parameters, among which bleeding on probing (BOP), biofilm accumulation (IP), clinical attachment level (CAL), recession reduction (RecRed), and the percentage of combined defect coverage (%CDC). Patient-reported outcomes such as post-surgery pain and discomfort, time to recover, the decrease of dentin hypersensitive, and aesthetics will be gathered. A professional assessment will be carried out regarding the aesthetic parameters. All these evaluations will be performed at the baseline and three and six months postoperatively.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05916716
Study type Interventional
Source Universidade Estadual Paulista Júlio de Mesquita Filho
Contact Mauro P Santamaria, PhD
Phone (12) 39479055
Email mauro.santamaria@unesp.br
Status Recruiting
Phase N/A
Start date August 1, 2022
Completion date December 1, 2023
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT05591326 - The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients With Gingival Recession. N/A
Recruiting NCT06000228 - Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage N/A
Recruiting NCT05563428 - Free Gingival Graft Versus Connective Tissue Graft N/A
Completed NCT04854902 - Cyanoacrylate Use in Free Gingival Graft N/A
Active, not recruiting NCT05682274 - Effect of Restoration Margin Level in the Treatment of Gingival Recession Associated With Non-carious Cervical Lesion N/A
Completed NCT05822323 - Effect of Botulinum Toxin-A on Free Gingival Graft N/A
Not yet recruiting NCT04729569 - Gingival Response and Marginal Adaptation of Zirconia Crowns With Two Subgingival Margin Designs N/A
Not yet recruiting NCT06228534 - Root Coverage With Tunneling Technique With Connective Tissue Versus Coronal Advancement Flap Technique. N/A
Completed NCT06197893 - Modified Sling and Conventional Suture Techniques in Free Gingival Graft Operations N/A
Recruiting NCT05850065 - Assessment of Gingival Health Following Rubber-Dam Isolation N/A
Completed NCT04718545 - Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects N/A
Recruiting NCT05990049 - Hyaluronic Acid and Free Gingival Graft Healing Phase 3
Completed NCT03425695 - Free Gingival Graft Adjunct With Low Level Laser Therapy N/A
Completed NCT06373783 - Ultrasonographic Evaluation of the Connective Tissue Grafts Obtained With Two Different Methods in Root Coverage N/A
Not yet recruiting NCT06432439 - Impact of Microneedling on Coverage of RT1 Gingival Recession in Thin Phenotype. N/A
Not yet recruiting NCT06030947 - Effectiveness of Meshed Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects N/A
Enrolling by invitation NCT06065774 - Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial N/A
Recruiting NCT06404762 - Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects N/A
Completed NCT04198376 - The Laterally Closed Tunnel Versus Modified Coronally Advanced Tunnel for Mandibular Anterior Gingival Recession Defects N/A
Completed NCT03200392 - Er,Cr:YSGG Laser For Recipient Bed Bio-modification And Connective Tissue Harvesting in Treatment of Gingival Recession N/A