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Clinical Trial Summary

Giant cell tumors are mostly benign tomoral processes, most often responsible for areas of osteolysis in the metaphysoepiphyseal area of long bones, representing 5-6% of primary bone tumors. The bone weakening induced by these beaches leads to pain and risk of fracture, and this is what leads the patient to consult. These tumors are found particularly in the young adult population between 20 and 40 years old, are locally aggressive, but malignant transformations and metastases (pulmonary) are quite rare. In this study, the investigators wish to retrospectively study the oral care of patients who presented with a giant cell tumor and were treated with Denosumab at the University Hospital of Strasbourg and their associated oral follow-up


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05542524
Study type Observational
Source University Hospital, Strasbourg, France
Contact
Status Completed
Phase
Start date September 1, 2022
Completion date August 31, 2023

See also
  Status Clinical Trial Phase
Completed NCT00680992 - Study of Denosumab in Subjects With Giant Cell Tumor of Bone Phase 2
Completed NCT02948088 - Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project
Completed NCT06331104 - Network Pharmacology Prediction: Mechanism Study of Puerarin in the Treatment of Giant Cell Tumors of Bone