Gastroesophageal Reflux Disease (GERD) Clinical Trial
Official title:
Assessment of Esophageal Epithelium Integrity With Mucosal Impedance
Verified date | April 2017 |
Source | Vanderbilt University Medical Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Gastroesophageal reflux disease (GERD) is a common condition affecting more than 100 million adults in the U.S., and it significantly impacts patients' quality of life while imposing billions of dollars of direct and indirect costs each year upon our healthcare system. Current diagnostic tests for GERD are highly invasive and medically inadequate, and the goal of this project is to develop a novel, minimally invasive Mucosal Impedance technique for more accurate detection of GERD while reducing costs.
Status | Completed |
Enrollment | 15 |
Est. completion date | December 2016 |
Est. primary completion date | December 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Patients undergoing standard of care EGD with 48-hr pH testing by BRAVO - Previous diagnosis of reflux - At least 18 years of age Exclusion Criteria: - Those less than 18 years of age - Unable to give informed consent - Use of acid suppressive therapy within the last 10 days - Known history of Barrett's esophagus, gastric surgery, alcoholism, or significant motility condition |
Country | Name | City | State |
---|---|---|---|
United States | Vanderbilt University Medical Center | Nashville | Tennessee |
Lead Sponsor | Collaborator |
---|---|
Vanderbilt University Medical Center |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Measurement of lower esophageal impedance using mucosal impedance catheter | Mucosal impedance is obtained during routine care EGD and readings are compared to 48-hour Bravo capsule results. Mucosal impedance only takes one minute to perform during endoscopy. | During standard of care EGD |
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