Clinical Trials Logo

Clinical Trial Summary

High tibial osteotomy has been established as an efficient surgical intervention for young patients with uni-compartmental osteoarthritis of the knee. The principle of this surgery involves the realignment of the lower extremity to shift the load distribution from the medial compartment into the lateral compartment, thus leading to a decrease in symptoms related to medial compartment knee Osteoarthritis However, medial opening wedge high tibial osteotomy is also known to affect the posterior tibial slope angle , and it is reported that posterior tibial slope angle increases after medial opening wedge high tibial osteotomy .


Clinical Trial Description

High tibial osteotomy has been established as an efficient surgical intervention for young patients with uni-compartmental osteoarthritis of the knee. Medial opening wedge high tibial osteotomy is a well established surgery for patients with medial compartment knee osteoarthritis its most notable advantages include the precision of intraoperative angular correction, absence of the risk of peroneal nerve palsy in fibular osteotomy, absence of leg shortening, and preservation of bone stock. The principle of this surgery involves the realignment of the lower extremity to shift the load distribution from the medial compartment into the lateral compartment, thus leading to a decrease in symptoms related to medial compartment knee Osteoarthritis However, medial opening wedge high tibial osteotomy is also known to affect the posterior tibial slope angle , and it is reported that posterior tibial slope angle increases after medial opening wedge high tibial osteotomy . Satisfactory outcomes after surgery require optimal realignment both in the sagittal and coronal planes; in fact, poor realignment could lead to unsatisfactory clinical outcomes. An unintentional increase in posterior tibial slope angle after medial opening wedge high tibial osteotomy may influence knee kinematics and stability in the sagittal plane, which could lead to anterior translation of the tibial plateau, anterior shift of the tibiofemoral contact area, and subsequent redistribution of pressure into the posterior tibial plateau (particularly in knees with injured anterior cruciate ligaments). These conditions could result in articular cartilage degradation and further knee disability ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06288100
Study type Observational
Source Al-Azhar University
Contact
Status Completed
Phase
Start date January 1, 2023
Completion date January 1, 2024

See also
  Status Clinical Trial Phase
Completed NCT05241691 - Retrospective Evaluation of GGPSP's Safety and Clinical Performance for the Treatment of Lower Limbs Deformities.
Recruiting NCT02642848 - Clinical Outcomes of Open Wedge High Tibial Osteotomy With Autologous Bone Marrow or Adipose-derived Stem Cell Therapy N/A
Completed NCT01122017 - A Modified (Retro-Tubercle) Opening Wedge High Tibial Osteotomy Versus the Conventional Technique N/A
Recruiting NCT03065738 - Effect of RO On GB During TKR Severe Varus Deformity N/A
Recruiting NCT05936814 - Adductor Ratio in Severe Varus Gonarthrosis
Active, not recruiting NCT02256904 - RSA and Clinical Comparison of Anatomical and Mechanical Alignment in Total Knee Replacement N/A
Recruiting NCT05763901 - IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms N/A