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NCT05952050 Clinical Trial

Different Administration Routes of Dexmedetomidine on Postoperative Delirium

General Anesthesia Clinical Trial

Official title:
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing General Anesthesia

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05952050
Other study ID # US2023001
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date August 1, 2023
Est. completion date September 30, 2023

Study information
Verified date July 2023
Source Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Contact Weitao Chen
Phone 18025661798
Email 540138690@qq.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient. The current study aimed to compare the effect of different administration routes of dexmedetomidine on POD in elderly patients.

Recruitment information / eligibility
Status Recruiting
Enrollment 120
Est. completion date September 30, 2023
Est. primary completion date August 1, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 65 Years to 99 Years
Eligibility Inclusion Criteria: Older than 65 years; General anesthesia for more than two hours; Exclusion Criteria: -

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Dexmedetomidine
Different Administration Routes of Dexmedetomidine

Locations
Country Name City State
China Weitao Chen Zhongshan Guangdong

Sponsors (2)
Lead Sponsor Collaborator
Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd. Zhongshan Hospital Of Traditional Chinese Medicine

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary The frequency of delirium during the first 3 postoperative days 3 days
Secondary The incidence of postoperative sore throat 3 days
Secondary The incidence of sleep quality 3 days
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