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Clinical Trial Summary

A randomized clinical trial comparing endoscopic per-oral pyloromyotomy (POP) versus a control sham intervention (diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption) in patients with medically refractory gastroparesis.


Clinical Trial Description

A comparative effectiveness, single center (with two surgical units), randomized (1:1) study of endoscopic per-oral pyloromyotomy (POP) versus a control sham intervention (diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption) in adult patients with medically refractory gastroparesis who have failed management with dietary, lifestyle, and pharmacological therapy for at least six months. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05039424
Study type Interventional
Source The Cleveland Clinic
Contact Karim Kheniser
Phone 2164449941
Email khenisk@ccf.org
Status Recruiting
Phase N/A
Start date February 23, 2022
Completion date July 2026

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