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Fructose Effect on Neuroinflammation and Feelings — MOODYFRUCTOSE  

Gastro-Intestinal Disorder Clinical Trial

Official title:
Fructose Effect on Neuroinflammation and Feelings: Direct Action on the Brain or Indirect by the Intestinal Microbiota?

Clinical Trial Summary

Fructose is increasingly present in our food. The increase in its consumption is associated with the increase in the prevalence of several pathologies such as metabolic syndrome or hepatic steatosis. The effect of fructose consumption on brain health has been poorly studied. Studies in animal models show that diets enriched in fructose promote the development of emotional behavior disorders. Fructose malabsorption is also associated with changes in the microbiota that could also impact brain health. However, no human study to date has associated fructose malabsorption with changes in the gut microbiota and effects on brain health. The objective of this study is to study the emotional behavior of a population of healthy volunteers according to the presence or not of fructose malabsorption. Patients with fructose malabsorption are susceptible to gut dysbiosis without necessarily consuming high amounts of fructose.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05371067
Study type Interventional
Source University Hospital, Rouen
Contact Chloé Melchior
Phone 00332 32 88 89 90
Email Chloe.Melchior@chu-rouen.fr
Status Recruiting
Phase N/A
Start date June 8, 2021
Completion date August 8, 2022
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