Gastritis, Gastric Ulcer, and Duodenal Ulcer Clinical Trial
Official title:
Evaluation of the Efficacy of Concomitant Therapy for Eradication of Helicobacter Pylori
If we compare eradication rate of Helicobacter pylori divided to 4 groups: amoxicillin, rabeprazole, clarithromycin(AOC), amoxicillin, rabeprazole, metronidazole(AOM), treated with amoxicillin, rabeprazole for 5 day, followed by clarithromycin, metronidazole, rabeprazole for 5 days(sequential), amoxicillin, clarithromycin, metronidazole, rabeprazole(concomitant), then the eradication rate of concomitant group will be the highest.
- Subject: The patient of gastritis, gastric ulcer, and duodenal ulcer infected with
Helicobacter pylori
- 170 subjects per group
- Eradication regimens are as follows: AOC group, treated with amoxicillin, rabeprazole,
clarithromycin for 7 days; AOM group, treated with amoxicillin, rabeprazole,
metronidazole for 7 days; sequential group, treated with amoxicillin, rabeprazole for 5
day, followed by clarithromycin, metronidazole, rabeprazole for 5 days; concomitant
group, treated with amoxicillin, clarithromycin, metronidazole, rabeprazole for 7 days
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment