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Gastric Cancer clinical trials

View clinical trials related to Gastric Cancer.

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NCT ID: NCT03957564 Recruiting - Gastric Cancer Clinical Trials

Liquid Biopsy in Monitoring the Neoadjuvant Chemotherapy and Operation in Gastric Cancer

Start date: May 28, 2019
Phase: Phase 2
Study type: Interventional

To explore the clinical value of dynamic detection of circulating tumor cells(CTCs), circulating tumor DNA(ctDNA) and cell-free DNA(cfDNA) in neoadjuvant chemotherapy and operation of resectable or locally advanced gastric or gastro-oesophageal junction cancer.

NCT ID: NCT03957486 Completed - Gastric Cancer Clinical Trials

Effect of Arterial Cannulation on the Continuous and Non-invasive Hemoglobin Monitoring

Start date: May 14, 2019
Phase: N/A
Study type: Interventional

The primary purpose of this study is to investigate the effect of arterial cannulation on the continuous and non-invasive hemoglobin monitoring during laparoscopic gastrectomy

NCT ID: NCT03957460 Completed - Gastric Cancer Clinical Trials

Accuracy of Continuous and Non-invasive Hemoglobin Monitoring

Start date: November 20, 2017
Phase:
Study type: Observational [Patient Registry]

The primary purpose of this observational study is to investigate the accuracy on the continuous and non-invasive hemoglobin monitoring during laparoscopic gastrectomy.

NCT ID: NCT03952442 Recruiting - Gastric Cancer Clinical Trials

Nutrition Education Program for Postoperative Patients With Gastric Cancer

Start date: February 21, 2019
Phase: N/A
Study type: Interventional

Using randomized control study, explore the effect of standardized nutrition education program on the nutrition status and life quality of patients with gastric cancer after surgery.

NCT ID: NCT03950271 Active, not recruiting - Gastric Cancer Clinical Trials

SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine for Neoadjuvant Therapy of Gastric Adenocarcinoma/Gastroesophageal Junction Adenocarcinoma

Start date: January 20, 2020
Phase: Phase 2
Study type: Interventional

The aim of this study is to observe the efficacy and safety of immume checkpoint inhibitor PD-1 SHR1210 combined with Trastuzumab , Oxaliplatin and Capecitabine for Neoadjuvant Therapy of locally advanced resectable gastric and gastroesophageal junction adenocarcinoma.

NCT ID: NCT03941626 Recruiting - Gastric Cancer Clinical Trials

Autologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies

Start date: September 1, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This is a single arm, open-label, uni-center, phase I-II study to evaluate the safety and effectiveness of CAR-T/TCR-T cell immunotherapy in treating with different malignancies patients.

NCT ID: NCT03941561 Recruiting - Gastric Cancer Clinical Trials

S-1 for 9 Months Versus 1 Year for Stage II Gastric Cancer (SMAC)

Start date: January 1, 2019
Phase: Phase 3
Study type: Interventional

The study aims to compare the efficacy and safety of S-1 for 9 months versus S-1 for 1 year as adjuvant chemotherapy after D2 resection in patients with gastric cancer. Hypothesis: For gastric patients after D2 resection, S-1 for 9 months shows non-inferiority to S-1 for 1 year in disease-free survival(DFS), overall survival (OS) and safety.

NCT ID: NCT03939962 Active, not recruiting - Gastric Cancer Clinical Trials

Camrelizumab Combined With FOLFOX Neoadjuvant Therapy for Resectable Gastric and Gastroesophageal Junctional Adenocarcinoma

Start date: July 24, 2019
Phase: Phase 2
Study type: Interventional

The aim of this study is to observe the efficacy, safety, postoperative pathological response rate and survival benefit of immume checkpoint inhibitor PD-1 SHR1210 combined with chemotherapy in neoadjuvant therapy of locally advanced resectable gastric and gastroesophageal junction adenocarcinoma. In addition ,the investigators will explore the relationship between the immunophenotype of gastric cancer and the efficacy and drug resistance of immunotherapy combined with chemotherapy, and screen out biomarkers that can predict the efficacy of immunotherapy.

NCT ID: NCT03935893 Recruiting - Colorectal Cancer Clinical Trials

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Start date: December 3, 2019
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study to evaluate the efficacy of a non-myeloablative lymphodepleting preparative regimen followed by infusion of autologous TIL and high-dose aldesleukin in patients with locally advanced, recurrent, or metastatic cancer associated with one of the following cancer types: 1.) gastric/esophagogastric, 2.) colorectal, 3.) pancreatic, 4.) sarcoma, 5.) mesothelioma, 6.) neuroendocrine, 7.) squamous cell cancer, 8.) Merkle cell, 9.) mismatch repair deficient and/or microsatellite unstable cancers, and 10.) patients who have exhausted conventional systemic therapy options by using the objective response rate (ORR).

NCT ID: NCT03931044 Recruiting - Gastric Cancer Clinical Trials

Fluorescence Image-Guided Lymphadenectomy in Robotic Gastrectomy

IG-MIG
Start date: April 2019
Phase: N/A
Study type: Interventional

Gastric cancer is a worldwide challenge due to its spread, even epidemic in some areas, and the high mortality rates. Lymphadenectomy is considered the fundamental step during radical gastrectomy. In recent years, some researchers have tried to find a way to improve the surgical identification of the lymphatic drainage routes and lymph node stations. This new surgical frontier is the so called "navigation surgery". Among the different reported solutions, lately, the indocyanine green (ICG) has drawn attention. It is a fluorescence dye, that can be detected in the near infrared spectral band (NIR). The development of specific fluorescence imaging devices has allowed surgeons to visualize tumors, vascular and lymphatic structures. The Da Vinci Xi robotic system has an integrated imaging technology that has been used in colo-rectal and hepato-biliary surgery. However, up to date, the combined use of fluorescence imaging and robotic technology has not been evaluated during lymphadenectomy in gastric cancer. The general design of the present study is to evaluate the role of fluorescence imaging during robotic lymphadenectomy for gastric cancer.