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Gastric Cancer clinical trials

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NCT ID: NCT00661167 Completed - Gastric Cancer Clinical Trials

Phase II Study of ABI-007 for Gastric Cancer

Start date: April 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of tri-weekly ABI-007 for recurrence or unresectable gastric cancer patients who have received one prior regimen containing fluoropyrimidine and developed disease progression or recurrence.

NCT ID: NCT00660205 Completed - Gastric Cancer Clinical Trials

Venous Thromboembolism and Haemostatic Disturbances in Patients With Upper Gastrointestinal Cancer

GIVTE
Start date: February 2008
Phase: N/A
Study type: Observational

Cancer is a well known risk factor for venous thromboembolism (VTE) such as deep venous thrombosis (DVT) and pulmonary embolism (PE). Today we know that patients with adenocarcinomas of the gastro intestinal tract (GI-tract) often is in a hypercoagulable state. In our observational study we collect patients admitted to department with a tentative diagnosis of upper GI cancer including pancreas cancer and offer them flow doppler ultrasounds of both legs for diagnosis of DVT in the entire treatment time. The routine CT-scan of the chest is modified to diagnose PE. This will be compared with blood samples analysed for coagulation markers including D-dimer - a fibrinogen degradation product.

NCT ID: NCT00654160 Completed - Colorectal Cancer Clinical Trials

Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer

Start date: June 2008
Phase: Phase 1
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of irinotecan when given together with fluorouracil and leucovorin in treating patients with advanced gastrointestinal cancer.

NCT ID: NCT00639327 Completed - Gastric Cancer Clinical Trials

Second Line Chemotherapy for S-1 Refractory Advanced Gastric Cancer

Start date: March 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is compare overall survival of the test arm (CPT-11/S-1 combination) to the control arm (CPT-11 alone) in the subjects with S-1 refractory advanced gastric cancer.

NCT ID: NCT00629863 Completed - Gastric Cancer Clinical Trials

Endoscopic Ultrasound in Diagnosing Cancer in Patients With Localized Stomach Cancer or Esophageal Cancer

Start date: September 2004
Phase: N/A
Study type: Interventional

RATIONALE: Diagnostic procedures, such as endoscopic ultrasound, may help doctors learn the extent of stomach cancer or esophageal cancer. PURPOSE: This randomized clinical trial is studying how well endoscopic ultrasound works in diagnosing cancer in patients with localized stomach cancer or esophageal cancer.

NCT ID: NCT00613665 Completed - Lymphoma Clinical Trials

Safety and Immunogenicity of Chiron's Investigational H. Pylori Vaccine in Healthy Adults

Start date: February 2001
Phase: Phase 1
Study type: Interventional

This study was designed to investigate the safety and immunogenicity of Chiron's investigational H. pylori (HP3) vaccine

NCT ID: NCT00606619 Completed - Gastric Cancer Clinical Trials

Effects of Early Oral Feeding After Resection of Gastric Cancer

Start date: July 2008
Phase: Phase 3
Study type: Interventional

The aim of this study is to determine whether early oral feeding after curative resection for gastric cancer would be tolerable and give an effect on the recovery.

NCT ID: NCT00601705 Completed - Gastric Cancer Clinical Trials

Epirubicin, Oxaliplatin and Fluorouracil (EOF) in Cancer of the Esophagus, Gastroesophageal Junction, or Stomach

Start date: January 5, 2008
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as epirubicin, oxaliplatin, fluorouracil, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving chemotherapy and radiation therapy after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well giving combination chemotherapy, surgery, and radiation therapy works in treating patients with locoregionally advanced cancer of the esophagus, gastroesophageal junction, or stomach.

NCT ID: NCT00601510 Completed - Gastric Cancer Clinical Trials

Imatinib, Capecitabine, and Cisplatin in Treating Patients With Unresectable or Metastatic Stomach Cancer

Start date: November 2007
Phase: Phase 1
Study type: Interventional

RATIONALE: Imatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as capecitabine and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving imatinib together with combination chemotherapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of imatinib when given together with capecitabine and cisplatin in treating patients with unresectable or metastatic stomach cancer.

NCT ID: NCT00598546 Completed - Gastric Cancer Clinical Trials

Quality of Life Among Long-Term Survivors of Resected Gastric Cancer

Start date: September 2004
Phase: N/A
Study type: Observational

The purpose of this study is to find out how you feel about the quality of your life after having had surgery to remove your stomach tumor. Some patients continue to experience different problems after stomach surgery, even when the surgery was more than three years ago. The purpose of this study is to find out the specific things that may continue to affect patients' quality of life after a major operation.