Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Gait Disorders, Neurologic Clinical Trial

Official title:

Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00139321
• Other study ID #: RBM0260
• Status: Terminated
• Phase: N/A
• First received: August 30, 2005
• Last updated: January 7, 2013
• Start date: June 2004
• Est. completion date: July 2007

Study information

• Verified date: January 2013
• Source: Groupe Hospitalier Pitie-Salpetriere
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

Gait disorders and falls are frequent in patients with parkinsonian syndromes. In patients with Parkinson's disease (PD), these signs occurred later during the course of the disease in comparison to patients with other degenerative parkinsonian disorders. The pathophysiology of these symptoms are still not fully understood. Gait initiation challenges the balance control system as the body moves from an upright stable static posture to a continuously unstable gait. The aim of this study is to analyse the gait initiation process in patients with parkinsonian disorders.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 110
• Est. completion date: July 2007
• Est. primary completion date: July 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Patients able to walk without assistance

• Patients with Parkinson's disease or other degenerative parkinsonian syndromes (progressive supranuclear palsy [PSP], multiple system atrophy [MSA], corticobasal degeneration [CBD], etc.)

Exclusion Criteria:

• Other parkinsonian syndromes

• Dementia

• Neuroleptic treatment

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Gait Disorders, Neurologic
• Nervous System Diseases
• Parkinson Disease

Intervention

Device:
• Force platform and electromyography

Locations

Country	Name	City	State
France	Centre d'Investigation Clinique-Hôpital Pitié-Salpetriere	Paris

Sponsors (2)

Lead Sponsor	Collaborator
Groupe Hospitalier Pitie-Salpetriere	French National Institut of Health and Medical Research

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Biomechanical gait initiation parameters