Furcation Treatment With L-PRF and aPDT

Furcation Defects Clinical Trial

Official title:

Evaluation of Leukocyte Platelet Rich Fibrin With Antimicrobial Photodynamic Therapy in Treatment of Furcation Involvement: Randomised Clinical Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04842188
• Other study ID #: elamrousy2020
• Status: Completed
• Phase: N/A
• Start date: July 28, 2020
• Est. completion date: April 30, 2021

Study information

• Verified date: June 2021
• Source: Kafrelsheikh University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To treat grade II periodontally diseased furcation areas Leukocyte-Platelet Rich Fibrin (L-PRF) combined with antimicrobial Photo-Dynamic Therapy (a-PDT) was used.

Description:

randomized, triple-blinded study (patient, clinician and biostatistician). Twenty-four patients with Grade II furcation involvement were recruited in this study.

Control group only received L-PRF, while study group used a combination of L-PRF and aPDT Attachment level, pocket depth, horizontal component and gingival recession, also radiographic Bone depth, width, height and volume were were recorded at baseline and postoperatively after 6 months

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: April 30, 2021
• Est. primary completion date: April 12, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 32 Years to 48 Years

Eligibility

Inclusion Criteria:

• Grade II furcation involvement

• age range 18- 50 years

• 3 mm or more vertical probing depth

Exclusion Criteria:

• systemic disease

• abnormal clotting and bleeding

• smokers,

• root caries or restoration

• Grade II mobility

• periapical lesions

Related Conditions & MeSH terms

• Furcation Defects

Intervention

Procedure:
• L-PRF with aPDT
surgical open flap debridement followed by L-PRF with aPDT
• L-PRF
surgical open flap debridement followed by L-PRF alone

Locations

Country	Name	City	State
Egypt	faculty of dentistry, kafrelsheikh University	Kafr Ash Shaykh

Sponsors (1)

Lead Sponsor	Collaborator
Kafrelsheikh University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical evaluation of Vertical clinical attachment level VCAL	using periodontal probe in mm	6 months
Primary	clinical evaluation of vertical pocket depth VPD	using periodontal probe in mm	6 months
Primary	clinical evaluation of furcation horizontal component FHC	using periodontal probe in mm	6 months
Primary	clinical evaluation of gingival recession REC	using periodontal probe in mm	6 months